# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3132074 | B | Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli BL21 (DE3) using GTP as substrate assessed as disassembly of FtsZ at 40 to 80 uM by transmission electron microscopy | Mycobacterium tuberculosis | 1 | ALA3124890 | assay format | Scientific Literature | |
2. | ALA3132075 | B | Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli BL21 (DE3) using GTP as substrate assessed as reduction in aggregate formation at 40 to 80 uM by transmission electron microscopy | Mycobacterium tuberculosis | 1 | ALA3124890 | assay format | Scientific Literature | |
3. | ALA3132076 | B | Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli BL21 (DE3) using GTP as substrate assessed as reduction in protofilaments at 40 to 80 uM by transmission electron microscopy | Mycobacterium tuberculosis | 1 | ALA3124890 | assay format | Scientific Literature | |
4. | ALA3130011 | B | Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli BL21 (DE3) using GTP as substrate assessed as reduction in density and population of FtsZ polymers at 40 to 80 uM by transmission electron microscopy | Mycobacterium tuberculosis | 1 | ALA3124890 | assay format | Scientific Literature | |
5. | ALA3130012 | B | Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli BL21 (DE3) using GTP as substrate by spectrofluorimetric analysis | Mycobacterium tuberculosis | 3 | ALA3124890 | assay format | Scientific Literature | |
6. | ALA3130013 | F | Antibacterial activity against Mycobacterium tuberculosis W210 clinical isolate assessed as parasite growth inhibition after 6 days by microplate Alamar Blue assay | Mycobacterium tuberculosis | 4 | ALA3124890 | organism-based format | Scientific Literature | |
7. | ALA3130014 | F | Antibacterial activity against Mycobacterium tuberculosis TN587 clinical isolate harboring Kat G 3315T mutant assessed as parasite growth inhibition after 6 days by microplate Alamar Blue assay | Mycobacterium tuberculosis | 4 | ALA3124890 | organism-based format | Scientific Literature | |
8. | ALA3130015 | F | Antibacterial activity against Mycobacterium tuberculosis NHN382 clinical isolate harboring Kat G S315t mutant assessed as parasite growth inhibition after 6 days by microplate Alamar Blue assay | Mycobacterium tuberculosis | 4 | ALA3124890 | organism-based format | Scientific Literature | |
9. | ALA3130167 | A | Cytotoxicity against Vero cells after 3 days by Alamar Blue assay | Chlorocebus sabaeus | 64 | ALA3124890 | cell-based format | Scientific Literature | |
10. | ALA3130168 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv assessed as parasite growth inhibition after 6 days by microplate Alamar Blue assay | Mycobacterium tuberculosis | 67 | ALA3124890 | organism-based format | Scientific Literature | |
11. | ALA3865893 | F | Antibacterial activity against Mycobacterium tuberculosis H37Rv measured every 24 hrs for 7 days by MABA assay | Mycobacterium tuberculosis | 8 | ALA3865781 | assay format | Scientific Literature | |
12. | ALA3865894 | F | Antibacterial activity against Mycobacterium tuberculosis NHN382 clinical isolates measured every 24 hrs for 7 days by MABA assay | Mycobacterium tuberculosis | 8 | ALA3865781 | assay format | Scientific Literature | |
13. | ALA3865895 | F | Antibacterial activity against Mycobacterium tuberculosis TN587 clinical isolates measured every 24 hrs for 7 days by MABA assay | Mycobacterium tuberculosis | 8 | ALA3865781 | assay format | Scientific Literature | |
14. | ALA3865896 | F | Antibacterial activity against Mycobacterium tuberculosis W210 clinical isolates measured every 24 hrs for 7 days by MABA assay | Mycobacterium tuberculosis | 8 | ALA3865781 | assay format | Scientific Literature | |
15. | ALA4673716 | F | Antitubercular activity against mid logarithmic stage Mycobacterium tuberculosis H37Rv incubated for 6 days by alamar blue assay | Mycobacterium tuberculosis | 10 | ALA4673192 | organism-based format | Scientific Literature | |
16. | ALA4673720 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv incubated for 6 days by alamar blue assay | Mycobacterium tuberculosis | 56 | ALA4673192 | organism-based format | Scientific Literature |