| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3130022 | P | Half life in RPMI media at 10 uM by HPLC analysis | 3 | ALA3124904 | small-molecule physicochemical format | Scientific Literature | ||
| 2. | ALA3130023 | P | Half life in RPMI media at 1 uM by HPLC analysis | 1 | ALA3124904 | small-molecule physicochemical format | Scientific Literature | ||
| 3. | ALA3130024 | A | Half life in RPMI media at 10 uM by HPLC analysis in presence of fetal bovine serum | 3 | ALA3124904 | assay format | Scientific Literature | ||
| 4. | ALA3130025 | A | Half life in RPMI media at 1 uM by HPLC analysis in presence of fetal bovine serum | 1 | ALA3124904 | assay format | Scientific Literature | ||
| 5. | ALA3130026 | A | Half life in RPMI media at 10 uM by HPLC analysis in presence of human blood serum | 3 | ALA3124904 | assay format | Scientific Literature | ||
| 6. | ALA3130027 | A | Half life in RPMI media at 1 uM by HPLC analysis in presence of human blood serum | 1 | ALA3124904 | assay format | Scientific Literature | ||
| 7. | ALA3130028 | A | Selectivity ratio of IC50 for MEF to IC50 for human Jurkat T cells | 3 | ALA3124904 | cell-based format | Scientific Literature | ||
| 8. | ALA3130029 | A | Selectivity ratio of IC50 for MEF to IC50 for human SK-MEL-2 cells | 3 | ALA3124904 | cell-based format | Scientific Literature | ||
| 9. | ALA3130030 | A | Antiproliferative activity against MEF after 72 hrs by MTT assay | Mus musculus | 3 | ALA3124904 | cell-based format | Scientific Literature | |
| 10. | ALA3130031 | A | Selectivity ratio of IC50 for MEF to IC50 for human HeLa cells | 3 | ALA3124904 | cell-based format | Scientific Literature | ||
| 11. | ALA3130032 | F | Antiproliferative activity against human SK-MEL-2 cells after 72 hrs by MTT assay in presence of 5% FBS | Homo sapiens | 3 | ALA3124904 | cell-based format | Scientific Literature | |
| 12. | ALA3130034 | P | Dissociation constant, pKa of the compound | 3 | ALA3124904 | small-molecule physicochemical format | Scientific Literature | ||
| 13. | ALA3130035 | F | Selectivity ratio of IC50 for human SK-MEL-2 cells in presence of 5% FBS to IC50 for human SK-MEL-2 cells in presence of 10% FBS | Homo sapiens | 2 | ALA3124904 | cell-based format | Scientific Literature | |
| 14. | ALA3130036 | F | Inhibition of cap-independent HCV-IRES-induced translation in rabbit reticulocyte lysate at 500 nM after 1.5 hrs by luciferase reporter gene assay | Oryctolagus cuniculus | 18 | ALA3124904 | assay format | Scientific Literature | |
| 15. | ALA3130038 | B | Binding affinity to eIF4A1/2 in rabbit reticulocyte lysate assessed as inhibition of cap-dependent translation after 1.5 hrs by dual luciferase reporter gene assay | Oryctolagus cuniculus | 13 | ALA3124904 | assay format | Scientific Literature | |
| 16. | ALA3130040 | F | Antiproliferative activity against human Jurkat T cells after 72 hrs by MTT assay | Homo sapiens | 7 | ALA3124904 | cell-based format | Scientific Literature | |
| 17. | ALA3130042 | F | Antiproliferative activity against human SK-MEL-2 cells after 72 hrs by MTT assay in presence of 10% FBS | Homo sapiens | 9 | ALA3124904 | cell-based format | Scientific Literature | |
| 18. | ALA3130043 | F | Antiproliferative activity against human HeLa cells after 72 hrs by MTT assay | Homo sapiens | 5 | ALA3124904 | cell-based format | Scientific Literature | |
| 19. | ALA3130045 | F | Immunosuppressive activity in human Jurkat T cells assessed as inhibition of IL-2 transcription | Homo sapiens | 9 | ALA3124904 | cell-based format | Scientific Literature | |
| 20. | ALA3130046 | A | Antiproliferative activity against BAEC assessed as DNA synthesis level after 24 hrs by thymidine incorporation assay | Bos taurus | 9 | ALA3124904 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!