# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3130001 | A | MRT (0 to t) in ICR mouse at 50 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA3130002 | A | AUC (0 to t) in ICR mouse at 50 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
3. | ALA3130003 | A | Tmax in ICR mouse at 50 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA3130004 | A | Cmax in ICR mouse at 50 mg/kg, po | Mus musculus | 1 | organism-based format | Scientific Literature | ||
5. | ALA3130005 | F | Hypoglycemic activity in ICR mouse assessed as reduction of blood glucose AUC (0 to 120 mins) at 50 mg/kg, po qd administered for 3 days followed by glucose challenge for 40 mins on day 3 post last dose by OGTT relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
6. | ALA3130007 | F | Hypoglycemic activity in ICR mouse assessed as decrease in blood glucose level at 50 mg/kg, po after 4 hrs by OGTT relative to control | Mus musculus | 3 | organism-based format | Scientific Literature | ||
7. | ALA3130008 | F | Hypoglycemic activity in ICR mouse assessed as decrease in blood glucose level at 50 mg/kg, po after 2 hrs by OGTT relative to control | Mus musculus | 2 | organism-based format | Scientific Literature | ||
8. | ALA3130010 | B | Activation of PPAR-gamma (unknown origin) transfected in human U2OS cells assessed as increase in transcriptional activity at 10'-6 M after 24 hrs by luciferase reporter gene assay relative to rosiglitazone | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA3131381 | B | Activation of glucokinase (unknown origin) using glucose as substrate at 10 uM relative to control | Homo sapiens | 44 | single protein format | Scientific Literature |