# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3128927 | A | Plasma protein binding in rat plasma | Rattus norvegicus | 9 | cell-free format | Scientific Literature | ||
2. | ALA3128928 | A | Ratio of drug level in cerebrospinal fluid in Sprague-Dawley rat at 10 mg/kg, po to unbound fraction in rat plasma | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
3. | ALA3128929 | A | Ratio of drug level in brain to plasma in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
4. | ALA3128930 | A | Drug level in Sprague-Dawley rat cerebrospinal fluid at 10 mg/kg, po | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
5. | ALA3128931 | A | Drug level in Sprague-Dawley rat brain at 10 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
6. | ALA3128932 | A | Plasma concentration in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 5 | organism-based format | Scientific Literature | ||
7. | ALA3128933 | A | Activity at rat MDR1a assessed as ratio of permeability from apical to basolateral side over permeability from basolateral to apical side by cell based assay | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
8. | ALA3128934 | A | Activity at human MDR1 assessed as ratio of permeability from apical to basolateral side over permeability from basolateral to apical side by cell based assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
9. | ALA3128935 | P | Apparent permeability of the compound | 7 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA3128936 | F | Positive allosteric modulation of human muscarinic M1 receptor expressed CHO cells assessed as intrinsic potency of acetylcholine-induced calcium mobilization by FLIPR assay relative to control | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
11. | ALA3128937 | F | Positive allosteric modulation of human muscarinic M1 receptor expressed CHO cells assessed as intrinsic potency of acetylcholine-induced calcium mobilization by FLIPR assay | Homo sapiens | 20 | cell-based format | Scientific Literature |