# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3128933 | ADME | Activity at rat MDR1a assessed as ratio of permeability from apical to basolateral side over permeability from basolateral to apical side by cell based assay | Rattus norvegicus | 7 | ALA3124934 | cell-based format | Scientific Literature | |
2. | ALA3128934 | ADME | Activity at human MDR1 assessed as ratio of permeability from apical to basolateral side over permeability from basolateral to apical side by cell based assay | Homo sapiens | 7 | ALA3124934 | cell-based format | Scientific Literature | |
3. | ALA3128935 | Physicochemical | Apparent permeability of the compound | 7 | ALA3124934 | small-molecule physicochemical format | Scientific Literature | ||
4. | ALA3128936 | Functional | Positive allosteric modulation of human muscarinic M1 receptor expressed CHO cells assessed as intrinsic potency of acetylcholine-induced calcium mobilization by FLIPR assay relative to control | Homo sapiens | 17 | ALA3124934 | cell-based format | Scientific Literature | |
5. | ALA3128937 | Functional | Positive allosteric modulation of human muscarinic M1 receptor expressed CHO cells assessed as intrinsic potency of acetylcholine-induced calcium mobilization by FLIPR assay | Homo sapiens | 20 | ALA3124934 | cell-based format | Scientific Literature |