# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3129666 | F | Cognition enhancing effect against scopolamine-induced memory deficit in po dosed Kunming mouse assessed as increase in latency time administered 1 hr before training followed by scopolamine challenge for 7 days measured after 24 hrs by step-down passive avoidance test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
2. | ALA3129667 | B | Induction of amyloid beta (1 to 42) (unknown origin) disaggregation assessed as reduction of Cu2+-induced amyloid beta fibril formation at 25 uM after 24 hrs by thioflavin T fluorescence method | Homo sapiens | 3 | single protein format | Scientific Literature | ||
3. | ALA3129670 | B | Inhibition of human erythrocytes AChE-induced amyloid beta (1 to 40) aggregation at 100 uM by thioflavin T fluorescence method | Homo sapiens | 5 | assay format | Scientific Literature | ||
4. | ALA3129671 | B | Inhibition of Cu2+-induced amyloid beta (1 to 42) (unknown origin) aggregation at 25 uM after 24 hrs by thioflavin T fluorescence method | Homo sapiens | 5 | single protein format | Scientific Literature | ||
5. | ALA3129672 | B | Inhibition of self-induced amyloid beta (1 to 42) (unknown origin) aggregation at 25 uM after 24 hrs by thioflavin T fluorescence method | Homo sapiens | 5 | single protein format | Scientific Literature | ||
6. | ALA3129675 | F | Antioxidant activity assessed as trolox equivalent of APPH-induced radical scavenging activity at 1 to 10 uM preincubated for 15 mins followed by AAPH challenge measured every minute for 90 minutes by ORAC fluorescence assay | 30 | assay format | Scientific Literature | |||
7. | ALA3129676 | B | Inhibition of rat serum BuChE using butyrylthiocholine iodide as substrate at 50 uM after 15 mins by Ellman's method | Rattus norvegicus | 29 | single protein format | Scientific Literature | ||
8. | ALA3129678 | B | Inhibition of human erythrocytes AchE using acetylthiocholine iodide as substrate after 15 mins by Ellman's method | Homo sapiens | 29 | assay format | Scientific Literature | ||
9. | ALA3129680 | B | Inhibition of electric eel AchE using acetylthiocholine iodide as substrate after 15 mins by Ellman's method | Electrophorus electricus | 29 | single protein format | Scientific Literature | ||
10. | ALA3129682 | B | Inhibition of rat cortex homogenate AchE using acetylthiocholine iodide as substrate after 15 mins by Ellman's method | Rattus norvegicus | 29 | assay format | Scientific Literature |