| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3129592 | B | Ratio of IC50 for rat xanthine oxidase to IC50 for C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system | 2 | assay format | Scientific Literature | |||
| 2. | ALA3129594 | A | Plasma concentration in potassium oxonate-induced hyperuricemic Sprague-Dawley rat model at 10 mg/kg, po measured after 2 hrs | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA3129596 | F | Antihyperuricemic activity in potassium oxonate-induced hyperuricemic Sprague-Dawley rat model assessed as decrease of uric acid level in serum at 10 mg/kg, po measured after 1 hr relative to vehicle-treated control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA3129597 | F | Antihyperuricemic activity in potassium oxonate-induced hyperuricemic Sprague-Dawley rat model assessed as decrease of uric acid level in serum at 10 mg/kg, po measured after 2 hrs relative to vehicle-treated control | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA3129598 | A | Oral bioavailability in Han Wistar rat at 6 umol/kg | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA3129599 | A | Cmax in Han Wistar rat at 6 umol/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA3129600 | A | Volume of distribution at steady state in Han Wistar rat at 6 umol/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA3129601 | A | Half life in Han Wistar rat at 1 umol/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA3129602 | A | Clearance in Han Wistar rat at 1 umol/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA3129603 | A | Efflux ratio of apparent permeability from basolateral to apical side over apical to basolateral side in human Caco2 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 11. | ALA3129604 | A | Apparent permeability across basolateral side to apical side in human Caco2 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 12. | ALA3129605 | A | Apparent permeability across apical side to basolateral side in human Caco2 cells | Homo sapiens | 11 | cell-based format | Scientific Literature | ||
| 13. | ALA3129606 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 20 | assay format | Scientific Literature | ||
| 14. | ALA3129607 | P | Solubility of the compound in phosphate buffer at pH 7.4 | 22 | small-molecule physicochemical format | Scientific Literature | |||
| 15. | ALA3129612 | B | Inhibition of C-terminally FLAG-tagged human xanthine oxidase (amino acid 1 to 1333) expressed in baculovirus system after 15 mins by spectrophotometry | Homo sapiens | 35 | assay format | Scientific Literature | ||
| 16. | ALA3129614 | B | Inhibition of rat xanthine oxidase | Rattus norvegicus | 2 | single protein format | Scientific Literature |
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