| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3131531 | A | Cytotoxicity against human L3.6PL cells assessed as growth inhibition after 48 hrs by MTS assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3131532 | B | Inhibition of polyamine transport system in DFMO-treated human L3.6PL cells assessed as increase in spermine level at 7 uM after 48 hrs by HPLC analysis in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA3131533 | B | Inhibition of polyamine transport system in DFMO-treated human L3.6PL cells assessed as reduction in intracellular spermidine level at 7 uM after 48 hrs by HPLC analysis in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3131534 | B | Inhibition of polyamine transport system in DFMO-treated human L3.6PL cells assessed as reduction in intracellular putrescine level at 7 uM after 48 hrs by HPLC analysis in presence of spermidine and aminoguanidine | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3131535 | B | Inhibition of polyamine transport system in human L3.6PL cells assessed as reduction in intracellular spermidine level at 7 uM after 48 hrs by HPLC analysis in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3131536 | B | Inhibition of polyamine transport system in human L3.6PL cells assessed as reduction in intracellular spermidine level at 7 uM after 48 hrs by HPLC analysis in presence of aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3131537 | F | Cytotoxicity against DFMO-treated human L3.6PL cells assessed as growth at 7 uM after 48 hrs in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3131538 | B | Inhibition of polyamine transport system in DFMO-treated human L3.6PL cells assessed as intracellular spermidine to spermine molar ratio at 7 uM after 48 hrs by HPLC analysis in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3131744 | B | Inhibition of polyamine transport system in DFMO-treated human L3.6PL cells assessed as total polyamine level at 7 uM after 48 hrs by HPLC analysis in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA3131745 | F | Cytotoxicity against human L3.6PL cells assessed as growth at 7 uM after 48 hrs in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3131746 | B | Inhibition of polyamine transport system in human L3.6PL cells assessed as intracellular spermidine to spermine molar ratio at 7 uM after 48 hrs by HPLC analysis in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3131747 | B | Inhibition of polyamine transport system in human L3.6PL cells assessed as total polyamine level at 7 uM after 48 hrs by HPLC analysis in presence of spermidine and aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3131748 | F | Cytotoxicity against human L3.6PL cells assessed as growth at 7 uM after 48 hrs in presence of aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3131749 | B | Inhibition of polyamine transport system in human L3.6PL cells assessed as intracellular spermidine to spermine molar ratio at 7 uM after 48 hrs by HPLC analysis in presence of aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3131750 | B | Inhibition of polyamine transport system in human L3.6PL cells assessed as total polyamine level at 7 uM after 48 hrs by HPLC analysis in presence of aminoguanidine relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3131754 | B | Inhibition of polyamine transport system-mediated [3H]-spermidine uptake in DFMO-treated human L3.6PL cells after 48 hrs in presence of spermidine and aminoguanidine | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 17. | ALA3131755 | A | Cytotoxicity against human L3.6PL cells assessed as growth inhibition after 48 hrs by MTS assay in presence of aminoguanidine | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 18. | ALA3129558 | B | Competitive inhibition of polyamine transport system-mediated [3H]-spermidine uptake in DFMO-treated human L3.6PL cells after 15 mins by Lineweaver-Burk plot analysis in presence of aminoguanidine | Homo sapiens | 8 | assay format | Scientific Literature | ||
| 19. | ALA3129559 | B | Inhibition of polyamine transport system-mediated [3H]-spermidine uptake in DFMO-treated CHO cells after 48 hrs in presence of spermidine and aminoguanidine | Cricetulus griseus | 4 | cell-based format | Scientific Literature | ||
| 20. | ALA3129560 | A | Selectivity ratio of IC50 for polyamine transport-deficient CHO-MG cells to IC50 for CHO cells | Cricetulus griseus | 9 | cell-based format | Scientific Literature |
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