| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3131350 | Binding | Selectivity index, ratio of IC50 for human serum BuChE to IC50 for electric eel acetylcholinesterase type VI-S | 5 | ALA3124749 | assay format | Scientific Literature | ||
| 2. | ALA3132690 | Functional | Neuroprotective activity against Abeta1-42 peptide-induced neurotoxicity in rat C6 cells assessed as cell viability at 100 uM after 24 hrs by MTT assay | Rattus norvegicus | 7 | ALA3124749 | cell-based format | Scientific Literature | |
| 3. | ALA3132691 | Functional | Neuroprotective activity against Abeta1-42 peptide-induced neurotoxicity in rat C6 cells assessed as reduction in cell viability loss after 24 hrs by MTT assay | Rattus norvegicus | 4 | ALA3124749 | cell-based format | Scientific Literature | |
| 4. | ALA3132692 | Functional | Neuroprotective activity against H2O2-induced oxidative stress in mouse/rat NG108-15 cells assessed as cell viability at 100 uM incubated for 2 hrs prior to H2O2 challenge for 2 hrs by MTT assay | Not specified | 7 | ALA3124749 | cell-based format | Scientific Literature | |
| 5. | ALA3129627 | Functional | Neuroprotective activity against H2O2-induced oxidative stress in mouse/rat NG108-15 cells assessed as increase in cell viability at 1 uM incubated for 2 hrs prior to H2O2 challenge for 2 hrs by MTT assay | Not specified | 2 | ALA3124749 | cell-based format | Scientific Literature | |
| 6. | ALA3129628 | Binding | Inhibition of BuChE in human serum using butyrylthiocholine iodide as substrate measured every 30s for 5 mins by Ellman's spectrophotometric method | Homo sapiens | 7 | ALA3124749 | single protein format | Scientific Literature | |
| 7. | ALA3129629 | Binding | Inhibition of electric eel acetylcholinesterase type VI-S using acetylthiocholine iodide as substrate measured every 30s for 5 mins by Ellman's spectrophotometric method | Electrophorus electricus | 7 | ALA3124749 | assay format | Scientific Literature | |
| 8. | ALA3129630 | Functional | Antioxidant activity assessed as inhibition of ABTS radical cation formation after 15 mins by ABTS radical scavenging method | 7 | ALA3124749 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!