| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3130508 | A | Fraction unbound in human brain by equilibrium dialysis method | Homo sapiens | 1 | ALA3124933 | tissue-based format | Scientific Literature | |
| 2. | ALA3130509 | A | Fraction unbound in human plasma by equilibrium dialysis method | Homo sapiens | 3 | ALA3124933 | cell-free format | Scientific Literature | |
| 3. | ALA3130510 | A | Clearance in iv dosed Han Wistar rat | Rattus norvegicus | 12 | ALA3124933 | organism-based format | Scientific Literature | |
| 4. | ALA3132099 | A | Ratio of free drug level in brain to blood in Han Wistar rat at 30 mg/kg, po measured at 1 hr by LC-MS/MS analysis | Rattus norvegicus | 15 | ALA3124933 | organism-based format | Scientific Literature | |
| 5. | ALA3132100 | A | Ratio of total drug level in brain to blood in Han Wistar rat at 30 mg/kg, po measured at 1 hr by LC-MS/MS analysis | Rattus norvegicus | 15 | ALA3124933 | organism-based format | Scientific Literature | |
| 6. | ALA3132104 | P | Lipophilicity, log D of the compound at pH 7.4 | 41 | ALA3124933 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA3132105 | B | Inhibition of N-terminal 6-His-tagged full-length mouse 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF assay | Mus musculus | 42 | ALA3124933 | single protein format | Scientific Literature | |
| 8. | ALA3132106 | B | Inhibition of N-terminal 6-His-tagged full-length human 11beta-HSD1 assessed as conversion of cortisone to cortisol after 25 mins by competitive HTRF assay | Homo sapiens | 42 | ALA3124933 | single protein format | Scientific Literature | |
| 9. | ALA3132109 | P | Thermodynamic solubility of the compound in solid form at pH 7.4 | 36 | ALA3124933 | small-molecule physicochemical format | Scientific Literature | ||
| 10. | ALA3132110 | B | Inhibition of recombinant human 11beta-HSD1 using cortisone/[3H]-cortisone as substrate after 5 hrs by reverse-phase HPLC analysis | Homo sapiens | 19 | ALA3124933 | single protein format | Scientific Literature | |
| 11. | ALA3132111 | A | Oral bioavailability in Han Wistar rat | Rattus norvegicus | 16 | ALA3124933 | organism-based format | Scientific Literature |
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