| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3128748 | B | Reversible inhibition of recombinant his6-tagged DPP4 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate assessed as recovery activity at 0.01 uM preincubated up to 240 mins followed by substrate addition by dialysis assay | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 2. | ALA3128750 | B | Time-dependent inhibition of recombinant his6-tagged DPP4 (unknown origin) expressed in baculovirus expression system at 0.01 uM | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA3128752 | B | Selectivity ratio of IC50 for recombinant his6-tagged DPP8 (unknown origin) to IC50 for recombinant his6-tagged DPP4 (unknown origin) | Homo sapiens | 15 | assay format | Scientific Literature | ||
| 4. | ALA3128753 | B | Selectivity ratio of IC50 for recombinant his6-tagged DPP9 (unknown origin) to IC50 for recombinant his6-tagged DPP4 (unknown origin) | Homo sapiens | 15 | assay format | Scientific Literature | ||
| 5. | ALA3128754 | B | Inhibition of recombinant his6-tagged DPP9 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric analysis | Homo sapiens | 15 | assay format | Scientific Literature | ||
| 6. | ALA3128755 | B | Inhibition of recombinant his6-tagged DPP8 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric analysis | Homo sapiens | 15 | assay format | Scientific Literature | ||
| 7. | ALA3128756 | B | Inhibition of recombinant his6-tagged DPP4 (unknown origin) expressed in baculovirus expression system using Ala-pro-AMC as substrate by fluorometric analysis | Homo sapiens | 15 | assay format | Scientific Literature | ||
| 8. | ALA3128757 | F | Antidiabetic activity in C57BKS db/db mouse assessed as blood glucose AUC (0 to 120 mins) administered for 5 weeks followed by glucose challenge at 6 hrs starvation of post last dose by OGTT | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA3130756 | A | Inhibition of CYP2C9 (unknown origin) at 100 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 10. | ALA3130758 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3130759 | B | Inhibition of human ERG expressed in CHO-ZG cells after 20 mins by FluxOR thallium assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3130760 | A | Oral bioavailability in Sprague-Dawley rat at 20 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3130762 | A | Apparent clearance in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3130764 | A | Half life in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA3130765 | A | Half life in Sprague-Dawley rat at 20 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 16. | ALA3130768 | A | Mean residence time in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA3130769 | A | Mean residence time in Sprague-Dawley rat at 20 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3130772 | A | AUC (0 to infinity) in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA3130773 | A | AUC (0 to infinity) in Sprague-Dawley rat at 20 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3130776 | A | AUC (0 to t) in Sprague-Dawley rat at 5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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