Antitumor activity against mouse EAC cells allografted in Swiss albino mouse assessed as condensed nucleus in tumor cells at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth
Antitumor activity against mouse EAC cells allografted in Swiss albino mouse assessed as DNA fragmentation in tumor cells at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth
Antitumor activity against mouse EAC cells allografted in Swiss albino mouse assessed as formation of apoptotic bodies in tumor cells at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth by Giemsa staining
Antitumor activity against mouse EAC cells allografted in Swiss albino mouse assessed as membrane blebbing of tumor cells at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth by Giemsa staining
Antitumor activity against mouse EAC cells allografted in Swiss albino mouse assessed as irregular tumor cell shape at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth by Giemsa staining
Antitumor activity against mouse EAC cells allografted in Swiss albino mouse assessed as tumor cell shrinkage at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth
Ex vivo antiangiogenic activity in 2 days fertilized chicken embryo chorioallantoic membrane model assessed as inhibition of rVEGF165-induced angiogenesis at 10 uM after 72 hrs by photographic analysis relative to control
In vivo antiangiogenic activity in 12 days fertilized chicken embryo chorioallantoic membrane model assessed as inhibition of rVEGF165-induced angiogenesis at 10 uM by photographic analysis relative to control
Antiangiogenic activity in mouse EAC cells allografted Swiss albino mouse model assessed as decrease in microvessel density in peritoneum at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth by hematoxylin and eosin staining method
Antiangiogenic activity in mouse EAC cells allografted Swiss albino mouse model assessed as decrease in peritoneal angiogenesis at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth
Antitumor activity against mouse DLA cells allografted in Swiss albino mouse assessed as tumor regression at 75 mg/kg, ip administered alternate days total of 10 doses measured on day 35 relative to untreated control
Antitumor activity against mouse EAC cells allografted in Swiss albino mouse assessed as inhibition of tumor growth at at 75 mg/kg, ip 3 doses administered every alternate days after three days of tumor growth
Antitumor activity against ip dosed mouse EAC cells allografted in Swiss albino mouse assessed as decrease in body weight administered 3 doses every alternate days after three days of tumor growth