# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3135857 | Binding | Agonist activity at dog TGR5 receptor expressed in CHO cells assessed as cAMP accumulation after 30 mins by spectrophotometry | Canis lupus familiaris | 3 | ALA3132829 | cell-based format | Scientific Literature | |
2. | ALA3135858 | Functional | Agonist activity at human recombinant TGR5 receptor expressed in CHO cells assessed as cAMP accumulation after 30 mins by spectrophotometry | Homo sapiens | 3 | ALA3132829 | cell-based format | Scientific Literature | |
3. | ALA3135859 | ADME | Intrinsic clearance in dog liver microsomes at 1 uM after 60 mins by LC-MS/MS analysis | Canis lupus familiaris | 3 | ALA3132829 | assay format | Scientific Literature | |
4. | ALA3135860 | ADME | Intrinsic clearance in human liver microsomes at 1 uM after 60 mins by LC-MS/MS analysis | Homo sapiens | 10 | ALA3132829 | assay format | Scientific Literature | |
5. | ALA3135861 | Functional | Agonist activity at human recombinant TGR5 receptor expressed in doxycycline-induced CHO cells assessed as cAMP accumulation after 30 mins by spectrophotometry | Homo sapiens | 10 | ALA3132829 | cell-based format | Scientific Literature |