# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3134674 | Binding | Inhibition of recombinant human caspase-8 expressed in Escherichia coli using Ac-IETD-AMC as substrate preincubated for 30 mins before substrate addition measured after 2 hrs | Homo sapiens | 17 | ALA3132757 | assay format | Scientific Literature | |
2. | ALA3134675 | Binding | Inhibition of recombinant human caspase-7 expressed in Escherichia coli using Ac-DEVD-AMC as substrate preincubated for 30 mins before substrate addition measured after 2 hrs | Homo sapiens | 17 | ALA3132757 | assay format | Scientific Literature | |
3. | ALA3134676 | Binding | Inhibition of recombinant human caspase-6 expressed in Escherichia coli using Ac-VEID-AMC as substrate preincubated for 30 mins before substrate addition measured after 2 hrs | Homo sapiens | 17 | ALA3132757 | assay format | Scientific Literature | |
4. | ALA3134677 | Binding | Inhibition of recombinant human caspase-3 expressed in Escherichia coli using Ac-DEVD-AMC as substrate preincubated for 30 mins before substrate addition measured after 2 hrs | Homo sapiens | 17 | ALA3132757 | assay format | Scientific Literature | |
5. | ALA3134678 | Binding | Inhibition of recombinant human caspase-1 expressed in Escherichia coli using Ac-YVAD-AMC as substrate preincubated for 30 mins before substrate addition measured after 2 hrs | Homo sapiens | 17 | ALA3132757 | assay format | Scientific Literature | |
6. | ALA3134679 | Physicochemical | Lipophilicity, log P of the compound by HPLC method | 17 | ALA3132757 | small-molecule physicochemical format | Scientific Literature |