# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3136076 | B | Destabilization of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase assessed as increase in enzyme sensitivity to trypsin proteolysis at 2000 uM by SDS-PAGE mthod | Cryptosporidium hominis | 1 | ALA3132813 | single protein format | Scientific Literature | |
2. | ALA3136081 | B | Noncompetitive inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase by Lineweaver-Burk plot | Cryptosporidium hominis | 2 | ALA3132813 | single protein format | Scientific Literature | |
3. | ALA3136082 | B | Noncompetitive inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase assessed as effect on enzyme Km using NADPH substrate by steady state kinetic assay | Cryptosporidium hominis | 2 | ALA3132813 | single protein format | Scientific Literature | |
4. | ALA3136083 | B | Noncompetitive inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase assessed as reduction in enzyme Vmax using NADPH substrate by steady state kinetic assay | Cryptosporidium hominis | 2 | ALA3132813 | single protein format | Scientific Literature | |
5. | ALA3136084 | B | Noncompetitive mixed type inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase assessed as increase in enzyme Km using H2folate substrate by steady state kinetic assay | Cryptosporidium hominis | 2 | ALA3132813 | single protein format | Scientific Literature | |
6. | ALA3136203 | B | Noncompetitive mixed type inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase assessed as reduction in enzyme Vmax using H2folate substrate by steady state kinetic assay | Cryptosporidium hominis | 2 | ALA3132813 | single protein format | Scientific Literature | |
7. | ALA3136204 | B | Inhibition of DHFR activity of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase by steady state kinetic assay | Cryptosporidium hominis | 2 | ALA3132813 | single protein format | Scientific Literature |