# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3134994 | Binding | Ratio of IC50 for LSD1 in human THP1 cells to IC50 for LSD1 (unknown origin) | Homo sapiens | 1 | ALA3132811 | cell-based format | Scientific Literature | |
2. | ALA3134995 | ADME | Cytotoxicity against human THP1 cells after 24 hrs | Homo sapiens | 3 | ALA3132811 | cell-based format | Scientific Literature | |
3. | ALA3135135 | Binding | Inhibition of LSD1 in human THP1 cells assessed as CD86 level after 24 hrs by ELISA | Homo sapiens | 3 | ALA3132811 | cell-based format | Scientific Literature | |
4. | ALA3135141 | Binding | Inhibition of MAO-A (unknown origin) assessed as oxidative deamination of kynuramine to 4-hydroxyquinoline after 30 mins by fluorescence assay | Homo sapiens | 47 | ALA3132811 | single protein format | Scientific Literature | |
5. | ALA3135142 | Binding | Inhibition of LSD1 (unknown origin) using histone H3 (1 to 21) K4(Me1)-biotin peptide as substrate after 30 mins by HTRF assay | Homo sapiens | 71 | ALA3132811 | single protein format | Scientific Literature | |
6. | ALA4047447 | Binding | Inhibition of recombinant human N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using histone H3(1-21)K4(Me1) biotin peptide as substrate measured after 30 mins by TR-FRET assay | Homo sapiens | 19 | ALA4043241 | assay format | Scientific Literature | |
7. | ALA4047448 | Binding | Binding affinity to LSD1 (unknown origin) by SPR analysis | Homo sapiens | 19 | ALA4043241 | single protein format | Scientific Literature | |
8. | ALA4047451 | Binding | Inhibition of human ERG expressed in CHO cells by Ionworks electrophysiology method | Homo sapiens | 2 | ALA4043241 | cell-based format | Scientific Literature | |
9. | ALA4047452 | Binding | Inhibition of LSD1 in human THP1 cells assessed as increase in CD86 expression after 48 hrs by PerCP EF710 staining based flow cytometry | Homo sapiens | 3 | ALA4043241 | cell-based format | Scientific Literature | |
10. | ALA4310493 | Binding | Inhibition of LSD1 (unknown origin) | Homo sapiens | 25 | ALA4308861 | single protein format | Scientific Literature | |
11. | ALA4310494 | Binding | Inhibition of LSD1 in human THP1 cells assessed as induction of CD11b expression after 4 days by LIVE/DEAD violet staining based FACS analysis | Homo sapiens | 25 | ALA4308861 | cell-based format | Scientific Literature | |
12. | ALA4310495 | Binding | Inhibition of human ERG at 10 uM relative to control | Homo sapiens | 25 | ALA4308861 | single protein format | Scientific Literature | |
13. | ALA5123803 | Binding | Binding affinity to human LSD1/CoREST assessed as dissociation constant by competitive fluorescence polarization assay | Homo sapiens | 31 | ALA5120862 | protein complex format | Scientific Literature | |
14. | ALA5123804 | Binding | Inhibition of human LSD1/CoREST using histone H3 peptide as substrate by fluorescence polarization assay | Homo sapiens | 13 | ALA5120862 | protein complex format | Scientific Literature | |
15. | ALA5123833 | Functional | Antiproliferative activity against human RD cells assessed as inhibition of cell growth incubated for 24 hrs | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
16. | ALA5123834 | Functional | Antiproliferative activity against human RD cells assessed as inhibition of cell growth incubated for 72 hrs | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
17. | ALA5123835 | Functional | Antiproliferative activity against human RD cells assessed as inhibition of cell growth incubated for 144 hrs | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
18. | ALA5123836 | Functional | Antiproliferative activity against human Rh30 cells assessed as inhibition of cell growth incubated for 24 hrs | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
19. | ALA5123837 | Functional | Antiproliferative activity against human Rh30 cells assessed as inhibition of cell growth incubated for 72 hrs | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature | |
20. | ALA5123838 | Functional | Antiproliferative activity against human Rh30 cells assessed as inhibition of cell growth incubated for 144 hrs | Homo sapiens | 6 | ALA5120862 | cell-based format | Scientific Literature |