| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA682046 | B | In vitro inhibition of [35S]TBPS binding to Gamma-aminobutyric acid A receptor in rat brain cortical membranes in the presence of 5 uM GABA (low affinity) | Rattus norvegicus | 1 | ALA1130204 | cell membrane format | Scientific Literature | |
| 2. | ALA682047 | B | In vitro inhibition of [35S]TBPS binding to Gamma-aminobutyric acid A (GABA-A) receptor of rat brain cortical membranes in the presence of 5 uM GABA(high affinity) | Rattus norvegicus | 2 | ALA1130204 | cell membrane format | Scientific Literature | |
| 3. | ALA723623 | F | Percent of animals (n=8) not exhibiting PTZ-induced ( Pentylentetrazol protection) seizures 10 min following a 10 mg/kg ip dose of steroid. | Mus musculus | 30 | ALA1130204 | organism-based format | Scientific Literature | |
| 4. | ALA800811 | F | In vitro for inhibition of [35S]TBPS binding in rat brain cortical membranes in the presence of 5 uM GABA in two-component inhibition curve | Rattus norvegicus | 1 | ALA1130204 | cell membrane format | Scientific Literature | |
| 5. | ALA802271 | F | The maximum inhibitory potency was calculated by fitting [35S]TBPS inhibition data to a sigmoid function (rat brain cortical P2 membranes) | Rattus norvegicus | 1 | ALA1130204 | organism-based format | Scientific Literature | |
| 6. | ALA803377 | F | The maximum inhibitory potency was calculated by fitting [35S]TBPS inhibition data to a sigmoid function (rat brain cortical P2 membranes) (high affinity) | Rattus norvegicus | 4 | ALA1130204 | organism-based format | Scientific Literature | |
| 7. | ALA803379 | F | The maximum inhibitory potency was calculated by fitting [35S]TBPS inhibition data to a sigmoid function (rat brain cortical P2 membranes) (low affinity) | Rattus norvegicus | 3 | ALA1130204 | organism-based format | Scientific Literature | |
| 8. | ALA822947 | F | Steroid potentiation of 5% GABA responses in Xenopus oocytes expressing human alpha-1-beta-2-gamma-2L subunits of GABA-A receptor | Homo sapiens | 7 | ALA1130204 | cell-based format | Scientific Literature | |
| 9. | ALA822949 | F | Efficacy as fractional response (FR) relative to GABA maximum current elicited in the Xenopus oocytes | Homo sapiens | 5 | ALA1130204 | cell-based format | Scientific Literature | |
| 10. | ALA881729 | B | The slope value for efficacy and response | 1 | ALA1130204 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!