# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA701213 | Functional | Evaluated for K-ATP activity in terms of change in membrane potential through guinea pig bladder assay | Cavia porcellus | 68 | ALA1148324 | cell membrane format | Scientific Literature | |
2. | ALA701216 | Functional | Evaluated for K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay | Sus scrofa | 36 | ALA1148324 | assay format | Scientific Literature | |
3. | ALA878707 | Functional | K-ATP activity in terms of stable twitch response through field-stimulated landrace pig detrusor assay | Sus scrofa | 26 | ALA1148325 | assay format | Scientific Literature | |
4. | ALA699663 | Functional | Evaluated for K-ATP activity as in vitro bladder relaxation in spontaneous Landrace pig detrusor strips (SLPD) | Sus scrofa | 6 | ALA1148324 | assay format | Scientific Literature | |
5. | ALA699664 | Functional | Evaluated for K-ATP activity as in vitro bladder relaxation in spontaneous Landrace pig detrusor strips (SLPD) | Sus scrofa | 4 | ALA1148325 | assay format | Scientific Literature | |
6. | ALA846990 | Functional | Selectivity expressed as the ratio of pEC50 (SLPD) and pEC50 (FSLPD) | 6 | ALA1148324 | assay format | Scientific Literature | ||
7. | ALA846991 | Functional | Selectivity expressed as the ratio of pEC50 (SLPD) and pEC50 (FSLPD) | 4 | ALA1148325 | assay format | Scientific Literature | ||
8. | ALA908895 | Functional | Ability to open human urinary bladder Kir6.2 channel containing SUR2B in Ltk cells by FLIPR assay | Homo sapiens | 78 | ALA1137338 | cell-based format | Scientific Literature | |
9. | ALA908896 | Functional | Ability to open human urinary bladder Kir6.2 containing SUR2B in Ltk cells by FLIPR assay relative to P1075 | Homo sapiens | 71 | ALA1137338 | cell-based format | Scientific Literature | |
10. | ALA759786 | Functional | Evaluated for change in heart rate from baseline at a plasma concentration of 1.9 nM in pigs | Sus scrofa | 1 | ALA1148324 | organism-based format | Scientific Literature | |
11. | ALA759789 | Functional | Evaluated for change in heart rate from baseline at a plasma concentration of 24 nM in pigs | Sus scrofa | 1 | ALA1148324 | organism-based format | Scientific Literature | |
12. | ALA759791 | Functional | Evaluated for change in heart rate from baseline at a plasma concentration of 95 nM in pigs | Sus scrofa | 1 | ALA1148324 | organism-based format | Scientific Literature | |
13. | ALA763957 | Functional | Evaluated for change in mean arterial pressure from baseline at a plasma concentration of 1.9 nM in pigs | Sus scrofa | 1 | ALA1148324 | organism-based format | Scientific Literature | |
14. | ALA763960 | Functional | Evaluated for change in mean arterial pressure from baseline at a plasma concentration of 24 nM in pigs | Sus scrofa | 1 | ALA1148324 | organism-based format | Scientific Literature | |
15. | ALA764628 | Functional | Evaluated for change in mean arterial pressure from baseline at a plasma concentration of 95 nM in pigs | Sus scrofa | 1 | ALA1148324 | organism-based format | Scientific Literature | |
16. | ALA798105 | Functional | In vitro reduction in blood pressure relative to maximum achieved with the K-ATP standard P1075 in spontaneously hypertensive rat | Rattus norvegicus | 3 | ALA1148325 | tissue-based format | Scientific Literature |