| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA2341796 | B | Inhibition of human DNA polymerase mu using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 2. | ALA2341797 | B | Inhibition of human DNA polymerase lambda using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 3. | ALA2341798 | B | Inhibition of rat DNA polymerase beta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Rattus norvegicus | 1 | single protein format | Scientific Literature | ||
| 4. | ALA2341799 | B | Inhibition of human DNA polymerase epsilon using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA2341800 | B | Inhibition of human DNA polymerase delta using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 6. | ALA2341801 | B | Inhibition of calf DNA polymerase alpha using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Bos taurus | 1 | assay format | Scientific Literature | ||
| 7. | ALA2341802 | B | Inhibition of human DNA polymerase gamma using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 8. | ALA2339780 | F | Induction of apoptosis in p53 -/- human HCT116 cells assessed as apoptotic cells at 13.7 uM incubated for 24 hrs by TUNEL analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA2339781 | F | Induction of apoptosis in p53 +/+ human HCT116 cells assessed as apoptotic cells at 13.2 uM incubated for 24 hrs by TUNEL analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA2339782 | F | Induction of apoptosis in p53 +/+ human HCT116 cells assessed as apoptotic cells at 13.2 uM incubated for 24 hrs by TUNEL analysis relative to p53 -/- human HCT116 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA2339783 | F | Induction of apoptosis in p53 -/- human HCT116 cells assessed as DNA fragmentation at 13.7 uM incubated for 24 hrs by agarose gel electrophoresis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA2339784 | F | Induction of apoptosis in p53 +/+ human HCT116 cells assessed as DNA fragmentation at 13.2 uM incubated for 24 hrs by agarose gel electrophoresis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA2339785 | F | Cytotoxicity against MMS-induced p53 -/- human HCT116 cells assessed as reduction in clonogenic survival at 13.7 uM incubated for 24 hrs by WST-1 assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA2339786 | F | Cytotoxicity against MMS-induced p53 +/+ human HCT116 cells assessed as reduction in clonogenic survival at 13.2 uM incubated for 24 hrs by WST-1 assay relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA2339787 | F | Cytotoxicity against p53 -/- human HCT116 cells assessed as growth inhibition incubated for 24 hrs by WST-1 assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA2339788 | A | Cytotoxicity against human dermal fibroblasts | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA2339789 | F | Cytotoxicity against p53 -/- human HCT116 cells assessed as growth inhibition at 200 uM incubated for 24 hrs by WST-1 assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 18. | ALA2339790 | F | Cytotoxicity against p53 +/+ human HCT116 cells assessed as growth inhibition incubated for 24 hrs by WST-1 assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA2339791 | F | Cytotoxicity against p53 +/+ human HCT116 cells assessed as growth inhibition at 200 uM incubated for 24 hrs by WST-1 assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 20. | ALA2339792 | B | Inhibition of human DNA polymerase kappa using poly(dA)/oligo(dT)18 (A/T, 2/1)/dTTP DNA template-primer substrate measured at 37 degC for 60 mins | Homo sapiens | 1 | single protein format | Scientific Literature |
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