# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1781266 | Binding | Binding affinity to poly(dA-dT)n DNA assessed as change in melting temperature at 0.3:1 molar compound/DNA ratio by spectrophotometry | 11 | ALA1777802 | nucleic acid format | Scientific Literature | ||
2. | ALA1781267 | ADME | Cytotoxicity against rat L6 cells | Rattus norvegicus | 11 | ALA1777802 | cell-based format | Scientific Literature | |
3. | ALA1781268 | Functional | Antiparasitic activity against Trypanosoma brucei rhodesiense STIB900 | Trypanosoma brucei rhodesiense | 11 | ALA1777802 | organism-based format | Scientific Literature | |
4. | ALA1781269 | Functional | Antiparasitic activity against Plasmodium falciparum K1 | Plasmodium falciparum | 11 | ALA1777802 | organism-based format | Scientific Literature | |
5. | ALA1781270 | Toxicity | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Trypanosoma brucei rhodesiense STIB900 | 11 | ALA1777802 | cell-based format | Scientific Literature | ||
6. | ALA1781271 | Toxicity | Selectivity index, ratio of IC50 for rat L6 cells to IC50 for Plasmodium falciparum K1 | 11 | ALA1777802 | cell-based format | Scientific Literature | ||
7. | ALA1781273 | Functional | Ratio of compound IC50 to DAPI IC50 for Trypanosoma brucei rhodesiense STIB900 | Trypanosoma brucei rhodesiense | 5 | ALA1777802 | organism-based format | Scientific Literature |