| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA645793 | B | In vitro binding affinity against Alpha-1 adrenergic receptor using [3H]prazosin as radioligand | 20 | ALA1128605 | protein format | Scientific Literature | ||
| 2. | ALA649185 | A | Therapeutic index is the ratio of IC50 value for Alpha-1 adrenergic receptor to that for NMDA. | 1 | ALA1125775 | assay format | Scientific Literature | ||
| 3. | ALA645238 | B | Compound was tested for the binding affinity against Alpha-1 adrenergic receptor | 3 | ALA1125775 | protein format | Scientific Literature | ||
| 4. | ALA645239 | B | Binding affinity against alpha-1 adrenergic receptor | 14 | ALA1125775 | protein format | Scientific Literature | ||
| 5. | ALA644129 | B | Tested for the Alpha-1 adrenergic receptor affinity in a standard radioligand binding assay with [3H]- prazosin | 7 | ALA1126814 | protein format | Scientific Literature | ||
| 6. | ALA747078 | F | Tested for the NMDA antagonist activity using a functional assay, by protection of cultured hippocampus neurons from the toxic effects of extracellularly applied glutamate | 7 | ALA1126814 | tissue-based format | Scientific Literature | ||
| 7. | ALA745941 | F | N-methyl-D-aspartate glutamate receptor antagonistic activity in cell culture(CC)model | 16 | ALA1125775 | assay format | Scientific Literature | ||
| 8. | ALA798364 | F | In vitro inhibition of glutamate induced neuronal death in primary cultures of rat hippocampal neurons. | 20 | ALA1128605 | tissue-based format | Scientific Literature | ||
| 9. | ALA835748 | B | Selectivity between protection against glutamate-induced neuronal damage and alpha 1 adrenergic affinity | Rattus norvegicus | 14 | ALA1128605 | assay format | Scientific Literature | |
| 10. | ALA838932 | F | Ratio of the IC50s of the two assays (alpha1 adrenoceptor binding assay/GT functional assay) used as an estimate of Therapeutic Index | 7 | ALA1126814 | assay format | Scientific Literature | ||
| 11. | ALA848883 | A | Therapeutic index is the ratio of IC50 value for Alpha-1 adrenergic receptor to that for NMDA. | 10 | ALA1125775 | assay format | Scientific Literature | ||
| 12. | ALA899624 | B | Displacement of [3H]dofetilide from human HERG expressed in HEK293 cells | Homo sapiens | 17 | ALA1137458 | cell-based format | Scientific Literature | |
| 13. | ALA3737377 | B | Displacement of [3H]ifenprodil from Glun2B receptor (unknown origin) expressed in mouse L(tk-) cell membranes after 120 mins by scintillation counting analysis | Homo sapiens | 7 | ALA3734653 | cell-based format | Scientific Literature | |
| 14. | ALA3737380 | B | Displacement of [3H]-(+)-Pentazocine from sigma1 receptor in guniea pig brain cortex membranes by scintillation counting analysis | Cavia porcellus | 7 | ALA3734653 | cell membrane format | Scientific Literature | |
| 15. | ALA3737381 | B | Displacement of [3H]DTG from sigma2 receptor in rat liver membranes by scintillation counting analysis | Rattus norvegicus | 7 | ALA3734653 | cell membrane format | Scientific Literature | |
| 16. | ALA3737384 | B | Displacement of [3H]ifenprodil from human NR1a/NR2B receptor expressed in mouse L(tk-) cell membranes by scintillation counting analysis | Homo sapiens | 1 | ALA3734653 | cell-based format | Scientific Literature | |
| 17. | ALA3757723 | B | Displacement of [3H]ifenprodil from recombinant human GluN1a/GluN2B expressed in L(tk-)cells | Homo sapiens | 5 | ALA3751792 | cell-based format | Scientific Literature | |
| 18. | ALA3757724 | B | Binding affinity to sigma-1 receptor (unknown origin) by radioligand displacement assay | Homo sapiens | 7 | ALA3751792 | single protein format | Scientific Literature | |
| 19. | ALA3757725 | B | Binding affinity to sigma-2 receptor (unknown origin) by radioligand displacement assay | Homo sapiens | 7 | ALA3751792 | assay format | Scientific Literature | |
| 20. | ALA3804512 | B | Displacement of [3H]ifenprodil from recombinant human GluN2B expressed in mouse L(tk-) cell membranes incubated for 120 mins by microbeta scintillation counting analysis | Homo sapiens | 3 | ALA3797194 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!