| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3225178 | B | Antagonist activity at LPA receptor in human A431 cells assessed as inhibition of LPA-induced intracellular calcium mobilization at 10 uM by Fluo-3 AM-staining based FLIPR assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 2. | ALA3225179 | F | Competitive antagonist activity at human LPA1 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]GTPgammaS binding by liquid scintillation counting | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA3225180 | F | Competitive antagonist activity at N-terminal 3XHA-tagged human LPA3 receptor overexpressed in CHO cells assessed as inhibition of LPA-induced [35S]GTPgammaS binding by liquid scintillation counting | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA3225181 | F | Antagonist activity at LPAR1/LPAR3 in rat glioma C62B cells assessed as inhibition of LPA-induced reduction in isoproterenol-stimulated [3H]cAMP accumulation by liquid scintillation counting | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA3225182 | F | Antagonist activity at LPAR3 in rat glioma C62B cells assessed as inhibition of LPA3 agonist-induced reduction in isoproterenol-stimulated [3H]cAMP accumulation by liquid scintillation counting | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA3225183 | A | Half life in Wistar rat at 20 mg/kg, iv by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3225184 | F | Antagonist activity at LPAR2 receptor (unknown origin) assessed as inhibition of LPA-induced [35S]GTPgammaS binding by liquid scintillation counting | Homo sapiens | 1 | assay format | Scientific Literature |
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