# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3224081 | P | Stability of the compound in 0.02M phosphate buffer assessed as drug decomposition at 0.06 umol at pH 7 after 10 days by HPLC analysis | 1 | small-molecule physicochemical format | Scientific Literature | |||
2. | ALA3224082 | A | Stability of the compound in bovine serum assessed as drug degradation at 37 degC measured for 24 hrs | Bos taurus | 1 | assay format | Scientific Literature | ||
3. | ALA3224083 | A | Prodrug activation in phosphate buffer assessed as Escherichia coli beta-glucuronidase-catalysed release of doxorubicin at 0.06 umol at pH 7 after 6 hrs by HPLC analysis | Escherichia coli | 1 | single protein format | Scientific Literature | ||
4. | ALA3224084 | F | Antiproliferative activity against human NCI-H661 cells assessed as inhibition of cell viability at 1000 nM after 3 days by XTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
5. | ALA3224085 | F | Antiproliferative activity against human NCI-H661 cells assessed as inhibition of cell viability after 3 days by XTT assay in presence of beta-glucuronidase | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
6. | ALA3224086 | F | Ratio of HMR1826 IC50 to compound IC50 for human NCI-H661 cells in presence of beta-glucuronidase | Homo sapiens | 1 | cell-based format | Scientific Literature |