# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3226398 | Binding | Inhibition of isoprenylcysteine carboxyl methyltransferase in human Jurkat cells assessed as mislocalization of GFP-K-Ras at 10 uM after 24 hrs by fluorescence microscopic analysis | Homo sapiens | 1 | ALA3217500 | cell-based format | Scientific Literature | |
2. | ALA3226400 | Binding | Un-competitive inhibition of human isoprenylcysteine carboxyl methyltransferase using [14C]SAM and N-acetyl-S-farnesyl-L-cysteine as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA3217500 | single protein format | Scientific Literature | |
3. | ALA3226401 | Binding | Activity at human isoprenylcysteine carboxyl methyltransferase using [14C]SAM by vapor diffusion assay relative to AFC | Homo sapiens | 39 | ALA3217500 | single protein format | Scientific Literature | |
4. | ALA3226402 | Binding | Inhibition of human isoprenylcysteine carboxyl methyltransferase using [14C]SAM and N-acetyl-S-farnesyl-L-cysteine as substrate after 30 mins by vapor diffusion assay | Homo sapiens | 1 | ALA3217500 | single protein format | Scientific Literature | |
5. | ALA3226403 | Binding | Inhibition of human isoprenylcysteine carboxyl methyltransferase using [14C]SAM and N-acetyl-S-farnesyl-L-cysteine as substrate at 10 uM after 30 mins by vapor diffusion assay | Homo sapiens | 40 | ALA3217500 | single protein format | Scientific Literature | |
6. | ALA3226404 | Binding | Competitive inhibition of human isoprenylcysteine carboxyl methyltransferase using [14C]SAM and N-acetyl-S-farnesyl-L-cysteine as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 1 | ALA3217500 | single protein format | Scientific Literature |