# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3223538 | B | Inhibition of MDM2/MDMX-p53 interaction in human A2780 CP70 cells expressing p53 mutant gene assessed as induction of p21 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
2. | ALA3223539 | B | Inhibition of MDM2/MDMX-p53 interaction in human A2780 CP70 cells expressing p53 mutant gene assessed as induction of p53 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
3. | ALA3223540 | B | Inhibition of MDM2/MDMX-p53 interaction in human A2780 CP70 cells expressing p53 mutant gene assessed as induction of MDM2 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
4. | ALA3223541 | B | Inhibition of MDM2/MDMX-p53 interaction in human A2780 cells expressing wild-type p53 assessed as induction of p21 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
5. | ALA3223542 | B | Inhibition of MDM2/MDMX-p53 interaction in human A2780 cells expressing wild-type p53 assessed as induction of p53 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
6. | ALA3223543 | B | Inhibition of MDM2/MDMX-p53 interaction in human A2780 cells expressing wild-type p53 assessed as induction of MDM2 protein expression at 0.2 to 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
7. | ALA3223544 | B | Inhibition of MDM2/MDMX-p53 interaction in human SJSA-1 cells expressing amplified MDM2 and wild-type p53 assessed as induction of p21 protein expression at 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
8. | ALA3223545 | B | Inhibition of MDM2/MDMX-p53 interaction in human SJSA-1 cells expressing amplified MDM2 and wild-type p53 assessed as induction of p53 protein expression at 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
9. | ALA3223546 | B | Inhibition of MDM2/MDMX-p53 interaction in human SJSA-1 cells expressing amplified MDM2 and wild-type p53 assessed as induction of MDM2 protein expression at 5 uM after 4 hrs by western blot analysis | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
10. | ALA3223547 | F | Growth inhibition of human MRK-NU-1 cells expressing amplified MDMX and wild-type p53 | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
11. | ALA3227584 | F | Growth inhibition of human SN40R2 cells expressing amplified MDM2 and p53 mutant gene | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature | |
12. | ALA3227585 | B | Inhibition of MDMX-p53 interaction (unknown origin) by ELISA | Homo sapiens | 25 | ALA3217694 | single protein format | Scientific Literature | |
13. | ALA3227586 | B | Inhibition of MDM2-p53 interaction (unknown origin) by ELISA | Homo sapiens | 36 | ALA3217694 | single protein format | Scientific Literature | |
14. | ALA3227587 | F | Growth inhibition of human SJSA1 cells expressing amplified MDM2 and wild-type p53 | Homo sapiens | 3 | ALA3217694 | cell-based format | Scientific Literature |