# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3222879 | B | Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 90 mins by fluorescence assay | Homo sapiens | 3 | protein complex format | Scientific Literature | ||
2. | ALA3222881 | B | Inhibition of Mycobacterium tuberculosis 20S proteasome open-gate mutant using Suc-LLVY-AMC as substrate at 1 mM preincubated for 30 mins followed by substrate addition measured after 90 mins by fluorescence assay | Mycobacterium tuberculosis | 2 | assay format | Scientific Literature | ||
3. | ALA3222882 | B | Inhibition of Mycobacterium tuberculosis 20S proteasome open-gate mutant chymotrypsin like activity using Suc-LLVY-AMC as substrate assessed as decrease in enzyme velocity up to 100 uM | Mycobacterium tuberculosis | 2 | assay format | Scientific Literature | ||
4. | ALA3222883 | B | Inhibition of human 20S proteasome using Suc-LLVY-AMC as substrate assessed as decrease in enzyme velocity | Homo sapiens | 2 | protein complex format | Scientific Literature | ||
5. | ALA3222884 | B | Inhibition of 20S proteasome in human HeLa cells expressing GFP-tagged ubiquitin G76V mutant at 23 uM after 16 hrs by fluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA3222886 | P | Half life in 100 fold molar excess of deuterated water in DMSO at 37 degC by [1H]-NMR analysis | 2 | small-molecule physicochemical format | Scientific Literature |