# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3222327 | B | Activation of beta-glucosidase L444P mutant in lymphoblasts derived from patients with Gaucher disease using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 10 to 100 uM after 3 days relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA3226286 | B | Activation of beta-glucosidase L444P mutant in lymphoblasts derived from patients with Gaucher disease using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 100 uM after 3 days | Homo sapiens | 1 | single protein format | Scientific Literature | ||
3. | ALA3226287 | B | Activation of beta-glucosidase N370S mutant in lymphoblasts derived from patients with Gaucher disease using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 100 nM after 3 days relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
4. | ALA3226288 | B | Activation of beta-glucosidase N370S mutant in lymphoblasts derived from patients with Gaucher disease using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 100 nM to 100 uM after 3 days | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA3226289 | B | Activation of beta-glucosidase N370S mutant in lymphoblasts derived from patients with Gaucher disease using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 1 uM after 3 days | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA3226291 | B | Activation of beta-glucosidase N370S mutant in lymphoblasts derived from patients with Gaucher disease using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 10 uM after 3 days | Homo sapiens | 2 | single protein format | Scientific Literature | ||
7. | ALA3226292 | B | Activation of beta-glucosidase L444P mutant in lymphoblasts derived from patients with Gaucher disease using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 10 uM after 3 days | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA3226293 | A | Cytotoxicity against human fibroblasts up to 300 uM after 24 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA3226608 | B | Inhibition of coffee beans alpha-galactosidase at 200 uM | Coffea arabica | 2 | single protein format | Scientific Literature | ||
10. | ALA3226609 | B | Inhibition of bovine liver beta-galactosidase at 200 uM | Bos taurus | 2 | assay format | Scientific Literature | ||
11. | ALA3226610 | B | Inhibition of almond beta-glucosidase at 200 uM | Prunus dulcis | 2 | single protein format | Scientific Literature | ||
12. | ALA3226611 | B | Inhibition of yeast alpha-glucosidase at 200 uM | Saccharomyces cerevisiae | 2 | assay format | Scientific Literature | ||
13. | ALA3226612 | B | Ratio of IC50 for human recombinant imiglucerase at pH 5.2 to IC50 for human recombinant imiglucerase at pH 7 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
14. | ALA3226614 | B | Inhibition of imiglucerase in human fibroblasts using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate at 200 uM after 24 hrs | Homo sapiens | 2 | single protein format | Scientific Literature | ||
15. | ALA3226615 | B | Competitive inhibition of human recombinant imiglucerase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 30 mins at pH 7 before substrate addition measured after 10 mins by Lineweaver-Burk or Dixon plot analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
16. | ALA3226616 | B | Competitive inhibition of human recombinant imiglucerase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 30 mins at pH 5.2 before substrate addition measured after 10 mins by Lineweaver-Burk or Dixon plot analysis | Homo sapiens | 4 | single protein format | Scientific Literature | ||
17. | ALA3226617 | B | Inhibition of human recombinant imiglucerase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 30 mins at pH 7 before substrate addition measured after 10 mins | Homo sapiens | 4 | single protein format | Scientific Literature | ||
18. | ALA3226618 | B | Inhibition of human recombinant imiglucerase using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate preincubated for 30 mins at pH 5.2 before substrate addition measured after 10 mins | Homo sapiens | 4 | single protein format | Scientific Literature |