# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3395896 | Binding | Inhibition of JNK1 (unknown origin) by time-resolved fluorescence assay | Homo sapiens | 17 | ALA3393060 | single protein format | Scientific Literature | |
2. | ALA3395898 | Binding | Inhibition of JNK3 (unknown origin) by time-resolved fluorescence assay | Homo sapiens | 17 | ALA3393060 | single protein format | Scientific Literature | |
3. | ALA3395902 | Binding | Inhibition of JNK3-mediated c-jun phosphorylation in rat INS1 cells | Rattus norvegicus | 9 | ALA3393060 | cell-based format | Scientific Literature | |
4. | ALA3396011 | ADME | Half life in rat | Rattus norvegicus | 1 | ALA3393060 | organism-based format | Scientific Literature | |
5. | ALA3396012 | ADME | Oral bioavailability in rat | Rattus norvegicus | 1 | ALA3393060 | organism-based format | Scientific Literature | |
6. | ALA3396013 | ADME | Ratio of drug level brain to plasma in rat | Rattus norvegicus | 1 | ALA3393060 | organism-based format | Scientific Literature | |
7. | ALA3226835 | Binding | Inhibition of JNK2 (unknown origin) using biotinylated ATF2 by HTRF method | Homo sapiens | 43 | ALA3217652 | single protein format | Scientific Literature | |
8. | ALA3226836 | Binding | Inhibition of JNK3 (unknown origin) using biotinylated ATF2 by HTRF method | Homo sapiens | 43 | ALA3217652 | single protein format | Scientific Literature | |
9. | ALA3226837 | Binding | Inhibition of JNK in rat INS cells assessed as inhibition of c-jun phosphorylation | Rattus norvegicus | 3 | ALA3217652 | cell-based format | Scientific Literature | |
10. | ALA3226838 | ADME | Half life in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 4 | ALA3217652 | organism-based format | Scientific Literature | |
11. | ALA3226839 | ADME | Clearance in Sprague-Dawley rat at 1 mg/kg, iv and 2 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 4 | ALA3217652 | organism-based format | Scientific Literature | |
12. | ALA3226840 | ADME | AUC in Sprague-Dawley rat at 2 mg/kg, po by LC-MS/MS analysis | Rattus norvegicus | 4 | ALA3217652 | organism-based format | Scientific Literature | |
13. | ALA3226841 | ADME | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg by LC-MS/MS analysis | Rattus norvegicus | 4 | ALA3217652 | organism-based format | Scientific Literature | |
14. | ALA3226842 | ADME | Plasma concentration in C57Bl6 mouse at 10 mg/kg after 2 hrs by LC-MS/MS analysis | Mus musculus | 4 | ALA3217652 | organism-based format | Scientific Literature | |
15. | ALA3226843 | ADME | Drug uptake in C57Bl6 mouse brain at 10 mg/kg after 2 hrs by LC-MS/MS analysis | Mus musculus | 4 | ALA3217652 | organism-based format | Scientific Literature | |
16. | ALA3226844 | ADME | Drug penetration in C57Bl6 mouse brain at 10 mg/kg by LC-MS/MS analysis relative to control | Mus musculus | 4 | ALA3217652 | organism-based format | Scientific Literature |