| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3225536 | B | Agonist activity at guinea pig histamine H2 receptor assessed as potentiation of histamine-induced response after 30 mins relative to histamine | Cavia porcellus | 7 | single protein format | Scientific Literature | ||
| 2. | ALA3225541 | B | Agonist activity at guinea pig atrium histamine H2 receptor assessed as potentiation of histamine-induced response after 30 mins | Cavia porcellus | 6 | single protein format | Scientific Literature | ||
| 3. | ALA3225542 | B | Antagonist activity at guinea pig ileum histamine H1 receptor assessed as inhibition of histamine-induced response after 10 to 15 mins | Cavia porcellus | 12 | tissue-based format | Scientific Literature | ||
| 4. | ALA3225553 | F | Antagonist activity at human recombinant histamine H3 receptor expressed in Sf9 cells coexpressing Galphai2,Gbeta1gamma2 and RGS4 assessed as inhibition of histamine-induced [gamma33P]GTP hydrolysis preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 5. | ALA3225555 | F | Antagonist activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 assessed as inhibition of histamine-induced [gamma33P]GTP hydrolysis preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay | Homo sapiens | 35 | cell-based format | Scientific Literature | ||
| 6. | ALA3225557 | B | Intrinsic activity at human recombinant histamine H3 receptor expressed in Sf9 cells coexpressing Galphai2,Gbeta1gamma2 and RGS4 preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay relative to histamine | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 7. | ALA3225905 | B | Intrinsic activity at human recombinant histamine H2 receptor-Gsalphas fusion protein expressed in Sf9 cells preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay relative to histamine | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 8. | ALA3225906 | B | Intrinsic activity at human recombinant histamine H1 receptor expressed in Sf9 cells coexpressing RGS4 preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay relative to histamine | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
| 9. | ALA3225907 | B | Agonist activity at human recombinant histamine H4 receptor-RGS19 fusion protein expressed in Sf9 cells coexpressing Galphai2,Gbeta1gamma2 preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 10. | ALA3225909 | B | Agonist activity at human recombinant histamine H2 receptor-Gsalphas fusion protein expressed in Sf9 cells preincubated for 2 mins before [gamma32P]GTP addition measured after 20 mins by steady-state GTPase activity assay | Homo sapiens | 8 | cell-based format | Scientific Literature |
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