# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3222686 | F | Neuroprotective activity in human SH-SY5Y cells under oxygen and glucose deprived condition assessed as protection against oxidative stress at 5 uM co-incubated for 4 hrs under anaerobic condition measured after 20 hrs by MTT assay relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
2. | ALA3222689 | F | Neuroprotective activity in human SH-SY5Y cells under oxygen and glucose deprived condition assessed as cell survival at 5 uM co-incubated for 4 hrs under anaerobic condition measured after 20 hrs by MTT assay relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA3222692 | F | Neuroprotective activity in human SH-SY5Y cells under serum-free condition assessed as protection against potassium-induced toxicity at 5 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
4. | ALA3222694 | F | Neuroprotective activity in human SH-SY5Y cells under serum-free condition assessed as cell survival at 5 uM after 24 hrs by MTT assay in presence of potassium relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
5. | ALA3226977 | F | Neuroprotective activity in human SH-SY5Y cells assessed as inhibition of potassium-induced Ca2+ increase at 10 uM preincubated for 15 mins followed by potassium addition measured for 14 seconds by fluorescence assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
6. | ALA3270056 | B | Inhibition of human Cav1.3 channel in human SH-SY5Y cells assessed as 70 mM K+ induced calcium elevation compound treated 15 mins before stimulus by Fluo-4/AM assay | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
7. | ALA3270057 | B | Inhibition of rat Cav1.2 channel in rat mesenteric artery assessed as relaxation of 70 mM K+ induced contraction | Rattus norvegicus | 24 | tissue-based format | Scientific Literature | ||
8. | ALA3270059 | F | Neuroprotective activity against K+ induced Ca2+ overload in human SH-SY5Y cells assessed as survival at 5 uM after 24 hrs by MTT assay (Rvb = 52.1 +/- 3.5%) | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
9. | ALA3265719 | F | Neuroprotective activity against K+ induced Ca2+ overload in human SH-SY5Y cells assessed as protection at 5 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
10. | ALA3265720 | F | Neuroprotective activity against rotenone-oligomycin A-induced oxidative stress in human SH-SY5Y cells assessed as survival at 5 uM co-incubated rot/oligo for 24 hrs by MTT assay (Rvb =65.6 +/- 1.3%) | Homo sapiens | 24 | cell-based format | Scientific Literature | ||
11. | ALA3265721 | F | Neuroprotective activity against rotenone-oligomycin A-induced oxidative stress in human SH-SY5Y cells assessed as protection at 5 uM co-incubated rot/oligo for 24 hrs by MTT assay relative to control | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
12. | ALA3265722 | F | Neuroprotective activity against rotenone-oligomycin A-induced oxidative stress in human SH-SY5Y cells assessed as survival incubated with rot/oligo for 8 hrs followed by treated with compound at 5 uM for 16 hrs by MTT assay (Rvb =70.6 +/- 1.8%) | Homo sapiens | 13 | cell-based format | Scientific Literature | ||
13. | ALA3265723 | F | Neuroprotective activity against rotenone-oligomycin A-induced oxidative stress in human SH-SY5Y cells assessed as protection incubated with rot/oligo for 8 hrs followed by treated with compound at 5 uM for 16 hrs by MTT assay relative to control | Homo sapiens | 13 | cell-based format | Scientific Literature |