# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3225697 | F | Antiproliferative activity against human HCT116 cells assessed as growth inhibition after 24 to 72 hrs by MTS assay | Homo sapiens | 4 | ALA3217663 | cell-based format | Scientific Literature | |
2. | ALA3225698 | F | Antiproliferative activity against human MCF7 cells assessed as growth inhibition after 24 to 72 hrs by MTS assay | Homo sapiens | 3 | ALA3217663 | cell-based format | Scientific Literature | |
3. | ALA3225699 | F | Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition after 24 to 72 hrs by MTS assay | Homo sapiens | 2 | ALA3217663 | cell-based format | Scientific Literature | |
4. | ALA3225700 | A | Antiproliferative activity against NHDF assessed as growth inhibition after 24 to 72 hrs by MTS assay | Homo sapiens | 3 | ALA3217663 | cell-based format | Scientific Literature | |
5. | ALA3225701 | A | Antiproliferative activity against NHLF assessed as growth inhibition after 24 to 72 hrs by MTS assay | Homo sapiens | 3 | ALA3217663 | assay format | Scientific Literature | |
6. | ALA3225702 | A | Antiproliferative activity against HUVEC assessed as growth inhibition after 24 to 72 hrs by MTS assay | Homo sapiens | 3 | ALA3217663 | cell-based format | Scientific Literature | |
7. | ALA3225703 | A | Antiproliferative activity against HMEC assessed as growth inhibition after 24 to 72 hrs by MTS assay | Homo sapiens | 3 | ALA3217663 | cell-based format | Scientific Literature | |
8. | ALA3226073 | T | Toxicity in mouse assessed as death at 0.03 to 3 mg/kg, iv once every 4 days for 3 injections | Mus musculus | 2 | ALA3217663 | organism-based format | Scientific Literature | |
9. | ALA3226074 | T | Toxicity in mouse assessed as body weight loss at 0.03 to 3 mg/kg, iv once every 4 days for 3 injections | Mus musculus | 1 | ALA3217663 | organism-based format | Scientific Literature | |
10. | ALA3226081 | F | Antitumor activity against human HCT116 cells xenografted in NCr-nu/nu mouse assessed as tumor weight reduction at 1.5 to 3 mg/kg, iv once every 4 days for 3 injections after 16 days of tumor cell transplantation | Homo sapiens | 2 | ALA3217663 | organism-based format | Scientific Literature | |
11. | ALA3226082 | F | Antitumor activity against human HCT116 cells xenografted in NCr-nu/nu mouse assessed as tumor weight reduction at 6 mg/kg, iv once every 4 days for 3 injections after 16 days of tumor cell transplantation | Homo sapiens | 1 | ALA3217663 | organism-based format | Scientific Literature | |
12. | ALA3226090 | A | Therapeutic index, ratio of GI50 for human HCT116 cells to GI50 for NHDF | Homo sapiens | 2 | ALA3217663 | cell-based format | Scientific Literature | |
13. | ALA3226091 | A | Therapeutic index, ratio of GI50 for human HCT116 cells to GI50 for NHLF | Homo sapiens | 2 | ALA3217663 | cell-based format | Scientific Literature | |
14. | ALA3226092 | A | Therapeutic index, ratio of GI50 for human HCT116 cells to GI50 for HMEC | Homo sapiens | 2 | ALA3217663 | cell-based format | Scientific Literature | |
15. | ALA3226093 | A | Therapeutic index, ratio of GI50 for human HCT116 cells to GI50 for HUVEC | Homo sapiens | 2 | ALA3217663 | cell-based format | Scientific Literature | |
16. | ALA3226094 | A | Half life in mouse serum | Mus musculus | 2 | ALA3217663 | assay format | Scientific Literature | |
17. | ALA5151308 | F | Cytotoxicity against human MCF7 cells incubated for 7 to 10 days by MTS assay | Homo sapiens | 2 | ALA5149986 | cell-based format | Scientific Literature | |
18. | ALA5151312 | F | Cytotoxicity against mouse L1210 cells assessed as inhibition in cell growth | Mus musculus | 5 | ALA5149986 | cell-based format | Scientific Literature | |
19. | ALA5151313 | F | Cytotoxicity against human HCT-116 cells assessed as inhibition in cell growth | Homo sapiens | 5 | ALA5149986 | cell-based format | Scientific Literature | |
20. | ALA5151314 | F | Cytotoxicity against human HCT116/VM46 cells assessed as inhibition in cell growth | Homo sapiens | 5 | ALA5149986 | cell-based format | Scientific Literature |