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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA3226073 T Toxicity in mouse assessed as death at 0.03 to 3 mg/kg, iv once every 4 days for 3 injections Mus musculus 2 ALA3217663 organism-based format Scientific Literature 2. ALA3226075 T Toxicity in mouse assessed as body weight loss at 3 mg/kg, iv once every 4 days for 3 injections Mus musculus 1 ALA3217663 organism-based format Scientific Literature 3. ALA3226076 T Toxicity in mouse assessed as tolerated dose compound treated once daily for 5 consecutive days Mus musculus 2 ALA3217663 organism-based format Scientific Literature 4. ALA3226077 T Toxicity in mouse assessed as body weight loss at 1 mg/kg, iv once every 4 days for 3 injections Mus musculus 1 ALA3217663 organism-based format Scientific Literature 5. ALA3226078 T Toxicity in mouse assessed as death at 0.5 mg/kg, iv led to the euthanization of mouse on day 9 Mus musculus 1 ALA3217663 organism-based format Scientific Literature 6. ALA3226079 T Toxicity in mouse assessed as body weight loss at 0.5 mg/kg, iv led to the euthanization of mouse on day 9 Mus musculus 1 ALA3217663 organism-based format Scientific Literature 7. ALA3226080 T Toxicity in mouse assessed as death at >= 1.5 mg/kg, iv compound treated once daily for 5 consecutive days Mus musculus 1 ALA3217663 organism-based format Scientific Literature 8. ALA3226081 F Antitumor activity against human HCT116 cells xenografted in NCr-nu/nu mouse assessed as tumor weight reduction at 1.5 to 3 mg/kg, iv once every 4 days for 3 injections after 16 days of tumor cell transplantation Homo sapiens 2 ALA3217663 organism-based format Scientific Literature 9. ALA3226083 F Antitumor activity against human HCT116 cells xenografted in NCr-nu/nu mouse assessed as tumor inhibition rate measured on day 41 at 6 mg/kg, iv once every 4 days for 3 injections after 16 days of tumor cell transplantation Homo sapiens 1 ALA3217663 organism-based format Scientific Literature 10. ALA3226085 F Antitumor activity against human PC3 cells xenografted in NCr-nu/nu mouse assessed as tumor weight reduction measured on day 22 at 1 mg/kg, iv once daily for 5 injections Homo sapiens 1 ALA3217663 organism-based format Scientific Literature 11. ALA3226086 T Toxicity in mouse assessed as body weight loss at 1 mg/kg, iv once daily for 5 injections Mus musculus 1 ALA3217663 organism-based format Scientific Literature 12. ALA3226087 A Plasma concentration in mouse at 6 mg/kg, iv after 30 mins Mus musculus 1 ALA3217663 organism-based format Scientific Literature 13. ALA3226094 A Half life in mouse serum Mus musculus 2 ALA3217663 assay format Scientific Literature 14. ALA5151312 F Cytotoxicity against mouse L1210 cells assessed as inhibition in cell growth Mus musculus 5 ALA5149986 cell-based format Scientific Literature 15. ALA5151313 F Cytotoxicity against human HCT-116 cells assessed as inhibition in cell growth Homo sapiens 5 ALA5149986 cell-based format Scientific Literature 16. ALA5151314 F Cytotoxicity against human HCT116/VM46 cells assessed as inhibition in cell growth Homo sapiens 5 ALA5149986 cell-based format Scientific Literature