# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3225868 | A | Cytotoxicity against HEK293T cells expressing rat SK3 assessed as cell viability at 10 uM after 48 hrs by MTT assay | Homo sapiens | 5 | ALA3217534 | cell-based format | Scientific Literature | |
2. | ALA3225869 | F | Effect on SK3 deficient HEK293T cell migration at 100 nM after 15 hrs by DAPI staining | Homo sapiens | 5 | ALA3217534 | cell-based format | Scientific Literature | |
3. | ALA3225870 | B | Inhibition of recombinant rat SK3 expressed in HEK293T cells assessed as inhibition of cell migration at 100 nM after 15 hrs by DAPI staining | Rattus norvegicus | 5 | ALA3217534 | cell-based format | Scientific Literature | |
4. | ALA3225871 | B | Inhibition of recombinant rat SK3 expressed in HEK293T cells assessed as decrease in channel current amplitude at 0 mV holding potential at 10 uM measured for 3 mins by patch clamp assay relative to control | Rattus norvegicus | 5 | ALA3217534 | cell-based format | Scientific Literature | |
5. | ALA3225872 | P | Solubility of the compound in water | 2 | ALA3217534 | small-molecule physicochemical format | Scientific Literature |