| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3222363 | T | Toxicity in Wistar rat assessed as total bilirubin at 100 mg/kg, po bid for 28 days (Rvb = 0.14 +/- 0.01 mg/dL) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA3222364 | T | Toxicity in Wistar rat assessed as alanine aminotransferase at 100 mg/kg, po bid for 28 days (Rvb = 20.78 +/- 1.31 U/L) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 3. | ALA3222365 | T | Toxicity in Wistar rat assessed as aspartate aminotransferase at 100 mg/kg, po bid for 28 days (Rvb = 147.16 +/- 11.75 U/L) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 4. | ALA3222366 | T | Toxicity in Wistar rat assessed as alkaline phosphatase at 100 mg/kg, po bid for 28 days (Rvb = 134.66 +/- 5.3 U/L) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 5. | ALA3222367 | F | Antiinflammatory activity in human whole blood assessed as inhibition of LPS-induced TNFalpha secretion by ELISA | Homo sapiens | 23 | tissue-based format | Scientific Literature | ||
| 6. | ALA3222368 | T | Toxicity in Wistar rat assessed as RBC count at 100 mg/kg, po bid for 28 days (Rvb = 7.38 +/- 0.11 10'6/ul) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA3222369 | T | Toxicity in Wistar rat assessed as WBC count at 100 mg/kg, po bid for 28 days (Rvb = 8.20 +/- 0.33 10'3/ul) | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 8. | ALA3222370 | B | Inhibition of human catalytic domain of TACE assessed as inhibit the cleavage of the substrate by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA3222371 | B | Inhibition of ADAM10 (unknown origin) using fluorescent substrate by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 10. | ALA3222372 | B | Inhibition of MMP1 (unknown origin) by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 11. | ALA3222373 | B | Inhibition of MMP2 (unknown origin) by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 12. | ALA3222374 | B | Inhibition of MMP3 (unknown origin) by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 13. | ALA3222375 | B | Inhibition of MMP7 (unknown origin) by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 14. | ALA3222376 | B | Inhibition of MMP8 (unknown origin) by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 15. | ALA3222377 | B | Inhibition of MMP9 (unknown origin) by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 16. | ALA3222378 | B | Inhibition of MMP13 (unknown origin) by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 17. | ALA3222379 | B | Inhibition of MMP14 (unknown origin) by fluorescence-based FRET assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 18. | ALA3222380 | B | Ratio of IC50 for human catalytic domain of TACE to IC50 for ADAM10 (unknown origin) | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 19. | ALA3222381 | B | Ratio of IC50 for human catalytic domain of TACE to IC50 for MMP1 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 20. | ALA3222382 | B | Ratio of IC50 for human catalytic domain of TACE to IC50 for MMP2 (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature |
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