| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3223375 | B | Inhibition of human NEP using N-Dansyl-D-Ala-Gly-p-nitro-Phe-Gly as substrate preincubated for 10 mins followed by substrate addition measured after 2 hrs by spectrophotometric analysis | Homo sapiens | 14 | ALA3217740 | single protein format | Scientific Literature | |
| 2. | ALA3223376 | B | Inhibition of ECE-1 in human NCO cells using Mca-Arg-Pro-Pro-GlyPhe-Ser-Ala-DpaOH as substrate after 45 mins by fluorescence assay | Homo sapiens | 4 | ALA3217740 | cell-based format | Scientific Literature | |
| 3. | ALA3223377 | B | Inhibition of human ACE-1 using Abz-Gly-p-nitro-Phe-Pro-OH as substrate preincubated for 10 mins followed by substrate addition measured after 17 hrs by spectrophotometric analysis | Homo sapiens | 4 | ALA3217740 | single protein format | Scientific Literature | |
| 4. | ALA3223378 | P | 1-octanol-PBS distribution coefficient, Log D of the compound at pH 7.4 after 2 hrs by LC-MS analysis | 5 | ALA3217740 | small-molecule physicochemical format | Scientific Literature | ||
| 5. | ALA3223379 | P | Solubility of the compound in PBS buffer at pH 7.4 after 24 hrs by LC-MS/MS analysis | 5 | ALA3217740 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA3223380 | A | Half life in rat plasma at 10 uM by LC-MS/MS | Rattus norvegicus | 5 | ALA3217740 | cell-free format | Scientific Literature |
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