# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3231655 | B | Antagonist activity at histamine H2 receptor in Charles River rat assessed as inhibition of histamine-mediated electrically stimulated uterine contraction at 20 ug/mL relative to histamine-treated placebo | Rattus norvegicus | 12 | single protein format | Scientific Literature | ||
2. | ALA3231656 | B | Antagonist activity at histamine H2 receptor in Hartley guinea pig atrium assessed as ratio of histamine concentration required in control to that required in presence of compound to increase atrium rate by 50 beats/min at 10 ug/mL | Cavia porcellus | 6 | single protein format | Scientific Literature | ||
3. | ALA3231657 | F | Antisecretory activity in Beagle dog assessed as inhibition of gastrin tetrapeptide-stimulated gastric acid secretion at 20 mg/kg, po administered 1 hr prior to gastrin tetrapeptide challenge measured every 30 mins for 90 mins relative to placebo control | Canis lupus familiaris | 33 | organism-based format | Scientific Literature | ||
4. | ALA3231659 | F | Antisecretory activity in Beagle dog assessed as inhibition of histamine-stimulated gastric acid secretion at 40 mg/kg, po administered 1 hr prior to histamine challenge measured every 30 mins for 90 mins relative to placebo control | Canis lupus familiaris | 33 | organism-based format | Scientific Literature |