| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3242718 | B | Inhibition of C-terminal His-6-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) at 50 uM by luminescence assay relative to control | Homo sapiens | 26 | assay format | Scientific Literature | ||
| 2. | ALA3242719 | B | Inhibition of SIRT2 (unknown origin) at 50 uM by luminescence assay relative to control | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 3. | ALA3242720 | B | Inhibition of SIRT3 (unknown origin) at 50 uM by luminescence assay relative to control | Homo sapiens | 26 | single protein format | Scientific Literature | ||
| 4. | ALA3242721 | B | Inhibition of C-terminal His-6-tagged recombinant human SIRT1 expressed in Escherichia coli BL21(DE3) by luminescence assay | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 5. | ALA3242722 | B | Inhibition of SIRT2 (unknown origin) by luminescence assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 6. | ALA3242723 | B | Inhibition of SIRT3 (unknown origin) by luminescence assay | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 7. | ALA3242725 | B | Inhibition of SIRT2-mediated alpha-tubulin acetylation in human NCI-H460 cells after 4 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3242726 | F | Induction of apoptosis in human NAMALWA cells assessed as viable cells at 10 uM after 16 hrs by annexin V-PE/DAPI-staining-based FACS analysis (Rvb = 86.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA3242727 | F | Induction of apoptosis in human NAMALWA cells assessed as early apoptotic cells at 10 uM after 16 hrs by annexin V-PE/DAPI-staining-based FACS analysis (Rvb = 1.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3242728 | F | Induction of apoptosis in human NAMALWA cells assessed as late apoptotic cells at 10 uM after 16 hrs by annexin V-PE/DAPI-staining-based FACS analysis (Rvb = 1.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA3242729 | F | Induction of apoptosis in human NAMALWA cells assessed as dead cells at 10 uM after 16 hrs by annexin V-PE/DAPI-staining-based FACS analysis (Rvb = 3.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3242730 | F | Induction of apoptosis in human NAMALWA cells assessed as viable cells at 25 uM after 16 hrs by annexin V-PE/DAPI-staining-based FACS analysis (Rvb = 86.6%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA3242731 | F | Induction of apoptosis in human NAMALWA cells assessed as early apoptotic cells at 25 uM after 16 hrs by annexin V-PE/DAPI-staining-based FACS analysis (Rvb = 1.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA3242882 | F | Induction of apoptosis in human NAMALWA cells assessed as late apoptotic cells at 25 uM after 16 hrs by annexin V-PE/DAPI-staining-based FACS analysis (Rvb = 1.2%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA3242883 | F | Induction of apoptosis in human NAMALWA cells assessed as dead cells at 25 uM after 16 hrs by annexin V-PE/DAPI-staining-based FACS analysis (Rvb = 3.4%) | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA3242885 | B | Selectivity ratio of IC50 for recombinant human SIRT1 to IC50 for SIRT2 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA3242888 | F | Antiproliferative activity against human Dakiki cells assessed as growth inhibition after 72 hrs by Cell Titer Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA3242889 | F | Antiproliferative activity against human Daudi cells assessed as growth inhibition after 72 hrs by Cell Titer Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA3242890 | F | Antiproliferative activity against human Mutu cells assessed as growth inhibition after 72 hrs by Cell Titer Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA3242891 | F | Antiproliferative activity against human Oku cells assessed as growth inhibition after 72 hrs by Cell Titer Glo assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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