#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3239920	B	Inhibition of SARS coronavirus papain-like protease (amino acids 1541 to 1855) expressed in Escherichia coli BL21 (DE3) cells assessed as decrease in AMC release using Z-RLRGG-AMC as substrate by multimode plate reader analysis	SARS coronavirus	31		cell-based format	Scientific Literature
2.	ALA3239921	B	Inhibition of SARS coronavirus papain-like protease Q270A mutant (amino acids 1541 to 1855) expressed in Escherichia coli BL21 (DE3) cells assessed as decrease in AMC release using Z-RLRGG-AMC as substrate by multimode plate reader analysis	SARS coronavirus	4		cell-based format	Scientific Literature
3.	ALA3239922	B	Inhibition of SARS coronavirus papain-like protease Q270E mutant (amino acids 1541 to 1855) expressed in Escherichia coli BL21 (DE3) cells assessed as decrease in AMC release using Z-RLRGG-AMC as substrate by multimode plate reader analysis	SARS coronavirus	4		cell-based format	Scientific Literature
4.	ALA3239923	B	Inhibition of SARS coronavirus papain-like protease Q270D mutant (amino acids 1541 to 1855) expressed in Escherichia coli BL21 (DE3) cells assessed as decrease in AMC release using Z-RLRGG-AMC as substrate by multimode plate reader analysis	SARS coronavirus	4		cell-based format	Scientific Literature
5.	ALA3239942	B	Inhibition of human coronavirus NL63 PLP2 (amino acids 1565 to 1894) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction of AMC release using Z-RLRGG-AMC as substrate by multimode plate reader analysis	Human coronavirus NL63	6		cell-based format	Scientific Literature
6.	ALA3238618	B	Inhibition of human coronavirus NL63 PLP2 (amino acids 1565 to 1894) expressed in Escherichia coli BL21 (DE3) cells assessed as reduction of AMC release using Z-RLRGG-AMC as substrate at 100 uM by multimode plate reader analysis	Human coronavirus NL63	6		cell-based format	Scientific Literature
7.	ALA3238619	F	Antiviral activity against SARS coronavirus infected in african green monkey Vero E6 cells assessed as cell viability after 48 hrs by Cell Titer-Glo luminescent assay	Severe acute respiratory syndrome-related coronavirus	9		organism-based format	Scientific Literature
8.	ALA3238620	A	Cytotoxicity against african green monkey Vero E6 cells assessed as cell viability after 48 hrs by Cell Titer-Glo luminescent assay	Chlorocebus sabaeus	6		cell-based format	Scientific Literature
9.	ALA3238621	A	Therapeutic index, ratio of CC50 for african green monkey Vero E6 cells to EC50 for SARS coronavirus infected in african green monkey Vero E6 cells		6		cell-based format	Scientific Literature
10.	ALA3238622	A	Cytotoxicity against human HEK293 cells assessed as cell viability after 48 hrs by Cell Titer-Glo luminescent assay	Homo sapiens	6		cell-based format	Scientific Literature
11.	ALA3238623	A	Metabolic stability in mouse liver microsomes assessed as parent compound remaining at 1 uM after 15 mins	Mus musculus	4		assay format	Scientific Literature
12.	ALA3238624	A	Half life in mouse liver microsomes at 1 uM	Mus musculus	4		assay format	Scientific Literature
13.	ALA3238625	B	Inhibition of SARS coronavirus papain-like protease (amino acids 1541 to 1855) expressed in Escherichia coli BL21 (DE3) cells assessed as decrease in AMC release using Z-RLRGG-AMC as substrate by serum shift assay based multimode plate reader analysis in presence of 5 to 20% human serum albumin	SARS coronavirus	6		cell-based format	Scientific Literature
14.	ALA5109239	B	Inhibition of full-length SARS-CoV-2 PLpro expressed in Escherichia coli BL21(DE3) using HCC-RLRGG-NH(CH2)4NH-DABCYL probe as substrate incubated for 30 mins by enzymatic assay	Severe acute respiratory syndrome coronavirus 2	10		assay format	Scientific Literature
15.	ALA5109240	B	Inhibition of full-length SARS-CoV-2 PLpro expressed in Escherichia coli BL21(DE3) using Ub-Rho as substrate incubated for 5 mins by enzymatic assay	Severe acute respiratory syndrome coronavirus 2	10		assay format	Scientific Literature