| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3239091 | B | Inhibition of human DGAT1 | Homo sapiens | 22 | single protein format | Scientific Literature | ||
| 2. | ALA3239092 | B | Inhibition of human DGAT2 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA3239093 | B | Inhibition of human ACAT2 | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 4. | ALA3239095 | F | Reduction of postprandial plasma triglyceride level in C57BL/6J mouse at 10 mg/kg, po administered 15 mins prior to corn oil bolus challenge measured after 2 hrs relative to vehicle-treated control | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 5. | ALA3239100 | A | Drug degradation in human plasma at 25 degC after 12 hrs | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 6. | ALA3293943 | B | Selectivity for human DGAT1 over human DGAT2 | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA3293944 | B | Selectivity for human DGAT1 over human ACAT | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA3293945 | A | Permeability in human Caco2 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 9. | ALA3293946 | P | Solubility of the compound | 3 | small-molecule physicochemical format | Scientific Literature | |||
| 10. | ALA3293947 | A | Clearance in rat liver hepatocytes measured per million cells | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
| 11. | ALA3293948 | A | Clearance in human liver hepatocytes measured per million cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA3293949 | A | Induction of CYP1A1 (unknown origin) at 30 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 13. | ALA3294180 | F | Reduction in triglycerides level in mouse at 10 mg/kg, po after 2 hrs by postprandial triglyceride assay | Mus musculus | 7 | organism-based format | Scientific Literature | ||
| 14. | ALA3294181 | A | Metabolic stability in human plasma assessed as compound loss measured at 12 hrs at 25 degC | Homo sapiens | 2 | cell-free format | Scientific Literature | ||
| 15. | ALA3294182 | B | Inhibition of human DGAT2 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting analysis | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA3294184 | B | Inhibition of human ACAT2 expressed in Sf9 insect cells using [14C]-oleoyl-CoA by scintillation counting analysis | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
| 17. | ALA3294188 | B | Inhibition of human DGAT1 expressed in Sf9 insect cells using 1,2-dioleoyl-sn-glycerol and [14C]-palmitoyl-CoA substrate by scintillation counting analysis | Homo sapiens | 46 | cell-based format | Scientific Literature |
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