# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3239091 | B | Inhibition of human DGAT1 | Homo sapiens | 22 | single protein format | Scientific Literature | ||
2. | ALA3239092 | B | Inhibition of human DGAT2 | Homo sapiens | 2 | single protein format | Scientific Literature | ||
3. | ALA3239093 | B | Inhibition of human ACAT2 | Homo sapiens | 5 | single protein format | Scientific Literature | ||
4. | ALA3239094 | B | Inhibition of mouse DGAT1 | Mus musculus | 19 | single protein format | Scientific Literature | ||
5. | ALA3239095 | F | Reduction of postprandial plasma triglyceride level in C57BL/6J mouse at 10 mg/kg, po administered 15 mins prior to corn oil bolus challenge measured after 2 hrs relative to vehicle-treated control | Mus musculus | 7 | organism-based format | Scientific Literature | ||
6. | ALA3239099 | A | AUC in rat at 10 mg/kg, po | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
7. | ALA3239101 | A | Metabolic stability in human plasma assessed as compound recovery at 25 degC after 6 days | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
8. | ALA3239102 | A | Plasma protein binding in rat | Rattus norvegicus | 2 | cell-free format | Scientific Literature | ||
9. | ALA3239103 | P | Solubility of the compound | 3 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA3239104 | A | Permeability across human Caco2 cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
11. | ALA3239105 | A | Clearance in rat hepatocytes assessed per million cells | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
12. | ALA3238959 | A | Clearance in human hepatocytes assessed per million cells | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA3242240 | A | Induction of CYP1A1 (unknown origin) at 30 uM | Homo sapiens | 2 | single protein format | Scientific Literature | ||
14. | ALA3242244 | A | Half life in rat at 10 mg/kg, po | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
15. | ALA3293945 | A | Permeability in human Caco2 cells | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
16. | ALA3293946 | P | Solubility of the compound | 3 | small-molecule physicochemical format | Scientific Literature | |||
17. | ALA3293947 | A | Clearance in rat liver hepatocytes measured per million cells | Rattus norvegicus | 4 | cell-based format | Scientific Literature | ||
18. | ALA3293948 | A | Clearance in human liver hepatocytes measured per million cells | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
19. | ALA3293949 | A | Induction of CYP1A1 (unknown origin) at 30 uM relative to control | Homo sapiens | 2 | single protein format | Scientific Literature | ||
20. | ALA3294180 | F | Reduction in triglycerides level in mouse at 10 mg/kg, po after 2 hrs by postprandial triglyceride assay | Mus musculus | 7 | organism-based format | Scientific Literature |