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# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3239990 | Binding | Inhibition of Candida glabrata DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPH | Nakaseomyces glabratus | 18 | ALA3232887 | assay format | Scientific Literature | |
2. | ALA3239991 | Binding | Inhibition of Candida albicans DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPH | Candida albicans | 18 | ALA3232887 | single protein format | Scientific Literature | |
3. | ALA3239992 | Binding | Inhibition of human DHFR using dihydrofolate as substrate preincubated for 5 mins followed by substrate addition in presence of NADPH | Homo sapiens | 16 | ALA3232887 | single protein format | Scientific Literature | |
4. | ALA3239993 | Functional | Antifungal activity against Candida glabrata SC5314 after 24 hrs by Alamar Blue assay | Nakaseomyces glabratus | 19 | ALA3232887 | organism-based format | Scientific Literature | |
5. | ALA3239994 | Functional | Antifungal activity against Candida albicans NCCLS84 after 24 hrs by XTT assay | Candida albicans | 18 | ALA3232887 | organism-based format | Scientific Literature | |
6. | ALA3239995 | ADME | Cytotoxicity against human MCF10 cells | Homo sapiens | 16 | ALA3232887 | cell-based format | Scientific Literature | |
7. | ALA3239996 | Binding | Selectivity ratio of IC50 for human DHFR to IC50 for Candida glabrata DHFR | 16 | ALA3232887 | assay format | Scientific Literature | ||
8. | ALA3239997 | Binding | Selectivity ratio of IC50 for human DHFR to IC50 for Candida albicans DHFR | 16 | ALA3232887 | assay format | Scientific Literature |
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