# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3241235 | B | Inhibition of Plasmodium falciparum HSP90 K313Q mutant expressed in yeast assessed as growth inhibition of host after 72 hrs | Plasmodium falciparum | 2 | ALA3232740 | assay format | Scientific Literature | |
2. | ALA3241236 | B | Inhibition of human HSP90beta expressed in yeast assessed as growth inhibition of host after 72 hrs | Homo sapiens | 2 | ALA3232740 | assay format | Scientific Literature | |
3. | ALA3241237 | B | Inhibition of human HSP90alpha expressed in yeast assessed as growth inhibition of host after 72 hrs | Homo sapiens | 2 | ALA3232740 | assay format | Scientific Literature | |
4. | ALA3241238 | B | Inhibition of Plasmodium falciparum HSP90 ISG-LGA mutant expressed in yeast assessed as growth inhibition of host after 72 hrs | Plasmodium falciparum | 1 | ALA3232740 | assay format | Scientific Literature | |
5. | ALA3241240 | B | Binding affinity to N-terminal FLAG-tagged Plasmodium falciparum recombinant HSP90 (1 to 223) expressed in Escherichia coli BL21(DE3) by microscale thermophoresis assay | Plasmodium falciparum | 5 | ALA3232740 | assay format | Scientific Literature | |
6. | ALA3241244 | B | Binding affinity to N-terminal FLAG-tagged Plasmodium falciparum recombinant HSP90 R98K mutant expressed in Escherichia coli BL21(DE3) by microscale thermophoresis assay | Plasmodium falciparum | 1 | ALA3232740 | assay format | Scientific Literature | |
7. | ALA3241245 | F | Antiplasmodial activity against Plasmodium falciparum NF54 infected in human erythrocytes assessed as growth inhibition by [3H]hypoxanthine incorporation assay | Plasmodium falciparum | 4 | ALA3232740 | organism-based format | Scientific Literature | |
8. | ALA3241246 | A | Cytotoxicity against rat L6 cells after 72 hrs by Alamar Blue assay | Rattus norvegicus | 4 | ALA3232740 | cell-based format | Scientific Literature | |
9. | ALA3241247 | U | Ratio of IC50 for rat L6 cells to IC50 for Plasmodium falciparum NF54 | 3 | ALA3232740 | cell-based format | Scientific Literature |