# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3242434 | F | Cytotoxicity against human CHP100 cells assessed as inhibition of cell survival at 4 uM after 24 hrs by MTT assay relative to control | Homo sapiens | 18 | ALA3232757 | cell-based format | Scientific Literature | |
2. | ALA3242435 | F | Cytotoxicity against human CHP100 cells assessed as inhibition of cell survival after 24 hrs by MTT assay | Homo sapiens | 18 | ALA3232757 | cell-based format | Scientific Literature | |
3. | ALA3242437 | B | Induction of HSP90B' (unknown origin)-mediated heat shock response expressed in human 293T cells coexpressing GFP assessed as heat shock index after overnight incubation by luciferase reporter gene assay relative to control | Homo sapiens | 38 | ALA3232757 | cell-based format | Scientific Literature | |
4. | ALA3242438 | F | Cytotoxicity against human NCI-H929 cells after 3 days by Alamar blue assay | Homo sapiens | 38 | ALA3232757 | cell-based format | Scientific Literature | |
5. | ALA3242439 | B | Induction of heat shock protein-mediated heat shock response in mouse 3T3-Y9-B12 cells assessed as heat shock index after 24 hrs by fluorescence assay relative to control | Mus musculus | 3 | ALA3232757 | cell-based format | Scientific Literature | |
6. | ALA3242440 | T | Toxicity in sc dosed mouse | Mus musculus | 2 | ALA3232757 | organism-based format | Scientific Literature | |
7. | ALA3242441 | F | Induction of heat shock activity in mouse assessed as upregulation of HSP72 protein level in spleen at 25 mg/kg, sc after 18 hrs by immunoblotting analysis | Mus musculus | 2 | ALA3232757 | organism-based format | Scientific Literature | |
8. | ALA3242582 | F | Induction of heat shock activity in mouse assessed as upregulation of HSP72 protein level in spleen at 40 mg/kg, sc after 18 hrs by immunoblotting analysis relative to control | Mus musculus | 1 | ALA3232757 | organism-based format | Scientific Literature | |
9. | ALA4010348 | F | Sensitization of TRAIL-induced apoptosis in human ACHN cells assessed as reduction in cell viability preincubated for 2 hrs followed by addition of TRAIL measured after 18 hrs by MTS assay | Homo sapiens | 37 | ALA4007460 | cell-based format | Scientific Literature | |
10. | ALA4010355 | F | Reduction cFLIP level in human ACHN cells at 125 to 1000 nM after 16 hrs by Western blot analysis | Homo sapiens | 2 | ALA4007460 | cell-based format | Scientific Literature | |
11. | ALA4010356 | A | Cytotoxicity in human ACHN cells assessed as viable cells at 1250 to 5000 nM after 48 hrs by MTS assay | Homo sapiens | 5 | ALA4007460 | cell-based format | Scientific Literature | |
12. | ALA4010357 | F | Induction of CHOP expression in human ACHN cells at 2.5 to 5 uM measured after 24 hrs by Western blotting method | Homo sapiens | 4 | ALA4007460 | cell-based format | Scientific Literature | |
13. | ALA4010358 | F | Induction of BIP expression in human ACHN cells at 2.5 to 5 uM measured after 24 hrs by Western blotting method | Homo sapiens | 4 | ALA4007460 | cell-based format | Scientific Literature | |
14. | ALA4010359 | F | Induction of HSP70 expression in human ACHN cells at 2.5 to 5 uM measured after 24 hrs by Western blotting method | Homo sapiens | 4 | ALA4007460 | cell-based format | Scientific Literature | |
15. | ALA4255612 | F | Induction of heat shock response in GFP-tagged human 293T cells at 1 to 5 uM after overnight incubation by luciferase reporter gene based luminometric method | Homo sapiens | 6 | ALA4251686 | cell-based format | Scientific Literature | |
16. | ALA4255615 | F | Cytotoxicity against human 293T cells assessed as reduction in cell viability at 1 to 5 uM after 72 hrs by resazurin dye based Alamar blue assay | Homo sapiens | 10 | ALA4251686 | cell-based format | Scientific Literature | |
17. | ALA4255616 | F | Cytotoxicity against human CHP100 cells assessed as reduction in cell viability after 24 hrs by resazurin dye based Alamar blue assay | Homo sapiens | 11 | ALA4251686 | cell-based format | Scientific Literature | |
18. | ALA4255617 | F | Cytotoxicity against human 293T cells assessed as reduction in cell viability after 72 hrs by resazurin dye based Alamar blue assay | Homo sapiens | 11 | ALA4251686 | cell-based format | Scientific Literature | |
19. | ALA4255618 | F | Induction of heat shock response in GFP-tagged human 293T cells after overnight incubation by luciferase reporter gene based luminometric method relative to control | Homo sapiens | 11 | ALA4251686 | cell-based format | Scientific Literature | |
20. | ALA4255619 | F | Ratio of induction of heat shock response in GFP-tagged human 293T cells to IC50 for cytotoxicity against human 293T cells | Homo sapiens | 9 | ALA4251686 | cell-based format | Scientific Literature |