#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3239420	F	Agonist activity at human TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assay	Homo sapiens	42		cell-based format	Scientific Literature
2.	ALA3239421	F	Agonist activity at mouse TGR5 expressed in Jurkat cells assessed as intracellular cAMP level after 1 hr by HTRF assay	Mus musculus	42		cell-based format	Scientific Literature
3.	ALA3239422	P	Thermodynamic solubility of the compound at pH 6.8		5		small-molecule physicochemical format	Scientific Literature
4.	ALA3239423	A	Inhibition of CYP3A4 (unknown origin)	Homo sapiens	17		single protein format	Scientific Literature
5.	ALA3239424	B	Inhibition of human ERG by patch clamp method	Homo sapiens	15		assay format	Scientific Literature
6.	ALA3239425	B	Agonist activity at TGR5 in mouse GLUTag cells assessed as secretion of GLP-1 after 2 hrs by HEK293 cell-based luciferase reporter gene assay in presence of DPP4 inhibitor PKF275 at 600 nM	Mus musculus	2		cell-based format	Scientific Literature
7.	ALA3239426	B	Agonist activity at TGR5 in mouse GLUTag cells assessed as secretion of GLP-1 after 2 hrs by HEK293 cell-based luciferase reporter gene assay in presence of DPP4 inhibitor PKF275 at 600 nM relative to N-(3,5-dichlorophenyl)-N-(1-(2-methoxyphenyl)ethyl)-3-methylisonicotinamide	Mus musculus	2		cell-based format	Scientific Literature
8.	ALA3239427	B	Agonist activity at TGR5 in human PBMC assessed as inhibition of LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation measured after 3 hrs by HTRF assay	Homo sapiens	2		single protein format	Scientific Literature
9.	ALA3239428	B	Agonist activity at TGR5 in human PBMC assessed as inhibition of LPS-induced TNFalpha production preincubated for 30 mins followed by LPS stimulation measured after 3 hrs by HTRF assay relative to N-(3,5-dichlorophenyl)-N-(1-(2-methoxyphenyl)ethyl)-3-methylisonicotinamide	Homo sapiens	2		single protein format	Scientific Literature
10.	ALA3239429	A	Intrinsic clearance in mouse liver microsomes after 60 mins by HPLC analysis	Mus musculus	11		assay format	Scientific Literature
11.	ALA3239430	A	Intrinsic clearance in human liver microsomes after 60 mins by HPLC analysis	Homo sapiens	1		assay format	Scientific Literature
12.	ALA3239431	A	Intrinsic clearance in rat liver microsomes after 60 mins by HPLC analysis	Rattus norvegicus	1		assay format	Scientific Literature
13.	ALA3239432	A	Inhibition of CYP2C9 (unknown origin)	Homo sapiens	2		single protein format	Scientific Literature
14.	ALA3239433	A	Inhibition of CYP2D6 (unknown origin)	Homo sapiens	2		single protein format	Scientific Literature
15.	ALA3239434	A	AUC in mouse at 5 mg/kg, iv	Mus musculus	2		organism-based format	Scientific Literature
16.	ALA3239435	A	AUC in mouse at 20 mg/kg, po	Mus musculus	2		organism-based format	Scientific Literature
17.	ALA3239436	A	Clearance in mouse at 5 mg/kg, iv	Mus musculus	2		organism-based format	Scientific Literature
18.	ALA3239437	A	Volume of distribution at steady state in mouse at 5 mg/kg, iv	Mus musculus	2		organism-based format	Scientific Literature
19.	ALA3239438	A	Cmax in mouse at 5 mg/kg, iv	Mus musculus	2		organism-based format	Scientific Literature
20.	ALA3239439	A	Cmax in mouse at 20 mg/kg, po	Mus musculus	2		organism-based format	Scientific Literature