| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3239012 | B | Inhibition of ATPase activity in Staphylococcus aureus GyrB tetramer in presence of Escherichia coli GyrA by ammonium molybdate/malachite green-based absorbance assay | Staphylococcus aureus | 39 | single protein format | Scientific Literature | ||
| 2. | ALA3239013 | B | Inhibition of ATPase activity in Escherichia coli GyrA/GyrB by ammonium molybdate/malachite green-based absorbance assay | Escherichia coli | 26 | assay format | Scientific Literature | ||
| 3. | ALA3239014 | B | Inhibition of ATPase activity in Escherichia coli ParC/ParE by ammonium molybdate/malachite green-based absorbance assay | Escherichia coli | 27 | assay format | Scientific Literature | ||
| 4. | ALA3239015 | B | Inhibition of ATPase activity in Escherichia coli ParE by ammonium molybdate/malachite green-based absorbance assay | Escherichia coli | 27 | assay format | Scientific Literature | ||
| 5. | ALA3239016 | F | Antibacterial activity against Streptococcus pneumoniae D39 NCTC 7466 assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | Streptococcus pneumoniae D39 | 27 | assay format | Scientific Literature | ||
| 6. | ALA3239017 | F | Antibacterial activity against methicillin-sensitive wild type Staphylococcus aureus assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | Staphylococcus aureus | 30 | organism-based format | Scientific Literature | ||
| 7. | ALA3239018 | F | Antibacterial activity against methicillin-resistant and quinoline-resistant Staphylococcus aureus assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | Staphylococcus aureus | 30 | organism-based format | Scientific Literature | ||
| 8. | ALA3239019 | F | Antibacterial activity against wild type Moraxella catarrhalis ATCC 43617 assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | Moraxella catarrhalis | 26 | organism-based format | Scientific Literature | ||
| 9. | ALA3239020 | F | Antibacterial activity against wild type Haemophilus influenzae Rd KW20 ATCC 51907 assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | Haemophilus influenzae Rd KW20 | 29 | assay format | Scientific Literature | ||
| 10. | ALA3239021 | F | Antibacterial activity against wild type Escherichia coli W3110 assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | Escherichia coli | 29 | organism-based format | Scientific Literature | ||
| 11. | ALA3239022 | F | Antibacterial activity against tolC efflux pump deficient Escherichia coli W3110 assessed as growth inhibition after 18 to 24 hrs by CLSI broth microdilution method | Escherichia coli | 27 | organism-based format | Scientific Literature | ||
| 12. | ALA3239023 | P | Octanol-phosphate buffer partition coefficient, log D of the compound at pH 7.4 after 1 hr by shake flask method | 18 | small-molecule physicochemical format | Scientific Literature | |||
| 13. | ALA3239024 | P | Solubility of the compound | 11 | small-molecule physicochemical format | Scientific Literature | |||
| 14. | ALA3239025 | A | Unbound fraction in human at 10 uM after 16 hrs by LC-MS/MS analysis | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 15. | ALA3239026 | P | Dissociation constant, pKa of the compound | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 16. | ALA4275017 | B | Inhibition of Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3) | Escherichia coli | 17 | assay format | Scientific Literature | ||
| 17. | ALA4275018 | B | Inhibition of Escherichia coli ParE | Escherichia coli | 17 | single protein format | Scientific Literature | ||
| 18. | ALA4275019 | B | Selectivity ratio of IC50 for Escherichia coli ParE to IC50 for Escherichia coli GyrB (1 to 220 residues) expressed in Escherichia coli BL21(DE3) | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 19. | ALA4275020 | F | Antibacterial activity against Pseudomonas aeruginosa PAO1 after 24 hrs by broth microdilution method | Pseudomonas aeruginosa | 17 | organism-based format | Scientific Literature | ||
| 20. | ALA4275021 | F | Antibacterial activity against Pseudomonas aeruginosa harboring MexABCDXY deletion mutant after 24 hrs by broth microdilution method | Pseudomonas aeruginosa | 17 | organism-based format | Scientific Literature |
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