| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3239261 | T | Genotoxicity in Salmonella typhimurium TA98 assessed as increase in number of revertants at 1.5 to 5000 ug/plate by Ames test in absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 2. | ALA3239262 | T | Genotoxicity in Salmonella typhimurium TA100 assessed as increase in number of revertants at 1.5 to 5000 ug/plate by Ames test in presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 3. | ALA3239263 | T | Genotoxicity in Salmonella typhimurium TA100 assessed as increase in number of revertants at 1.5 to 5000 ug/plate by Ames test in absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 4. | ALA3239265 | T | Toxicity in fasting C57BL/J6 mouse assessed as glucose lowering effect at 50 mg/kg, po after 30 to 360 mins | Mus musculus | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 5. | ALA3239266 | T | Toxicity in fasting C57BL/J6 mouse assessed as glucose level at 50 mg/kg, po measured after 60 mins | Mus musculus | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 6. | ALA3239304 | B | Activity of recombinant human pancreatic glucokinase assessed as glucose half-maximal saturation concentration | Homo sapiens | 18 | ALA3232870 | single protein format | Scientific Literature | |
| 7. | ALA3239305 | B | Activity of recombinant human pancreatic glucokinase assessed as glucose half-maximal activity | Homo sapiens | 1 | ALA3232870 | single protein format | Scientific Literature | |
| 8. | ALA3239306 | A | Cytotoxicity in Salmonella typhimurium TA98 at 1.5 to 5000 ug/plate in presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 9. | ALA3239307 | A | Cytotoxicity in Salmonella typhimurium TA98 at 1.5 to 5000 ug/plate in absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 10. | ALA3239308 | A | Cytotoxicity in Salmonella typhimurium TA100 at 1.5 to 5000 ug/plate in presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 11. | ALA3239309 | A | Cytotoxicity in Salmonella typhimurium TA100 at 1.5 to 5000 ug/plate in absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 12. | ALA3243400 | A | Metabolic stability in mouse liver microsomes assessed as compound remaining after 1 hr relative to control | Mus musculus | 1 | ALA3232870 | assay format | Scientific Literature | |
| 13. | ALA3243401 | F | Antidiabetic activity in po dosed C57BL/J6 db/db mouse assessed as reduction of glucose AUC preincubated for 30 mins followed by glucose challenge measured after 30 to 180 mins by oral glucose tolerance test | Mus musculus | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 14. | ALA3243402 | B | Activation of recombinant human pancreatic glucokinase using 10 mM glucose by spectrophotometry | Homo sapiens | 20 | ALA3232870 | single protein format | Scientific Literature | |
| 15. | ALA3243403 | F | Induction of 2-Deoxy-D-[3H]-glucose uptake in rat Hepatocytes using 5.5 mM glucose after 4 hrs by liquid scintillation counting | Rattus norvegicus | 15 | ALA3232870 | cell-based format | Scientific Literature | |
| 16. | ALA3243404 | F | Increase in 11 mM glucose-stimulated insulin secretion in mouse MIN6 cells measured for 1 hr by ELISA | Mus musculus | 1 | ALA3232870 | cell-based format | Scientific Literature | |
| 17. | ALA3243405 | F | Increase in 11 mM glucose-stimulated insulin secretion in Sprague-Dawley rat Pancreatic islet measured for 1 hr by ELISA | Rattus norvegicus | 1 | ALA3232870 | assay format | Scientific Literature | |
| 18. | ALA3243406 | F | Antidiabetic activity in glucose-treated C57BL/J6 db/db mouse assessed as reduction of glucose AUC at 50 mg/kg, po preincubated for 30 mins followed by glucose challenge measured after 30 to 180 mins by oral glucose tolerance test relative to control | Mus musculus | 10 | ALA3232870 | organism-based format | Scientific Literature | |
| 19. | ALA3243408 | T | Toxicity in C57BL/J6 db/db mouse assessed as hypoglycemia at 150 mg/kg, po | Mus musculus | 1 | ALA3232870 | organism-based format | Scientific Literature | |
| 20. | ALA3243409 | F | Antidiabetic activity in glucose-treated C57BL/J6 db/db mouse assessed as reduction of glucose AUC at 30 to 100 mg/kg, po administered for 2 weeks preincubated for 30 mins followed by glucose challenge measured after 30 to 180 mins by oral glucose tolerance test relative to control | Mus musculus | 1 | ALA3232870 | organism-based format | Scientific Literature |
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