# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3240640 | B | Binding affinity to human OX2 receptor in cell membrane by in vitro radioligand binding assay | Homo sapiens | 17 | ALA3232758 | cell-based format | Scientific Literature | |
2. | ALA3240641 | B | Binding affinity to human OX1 receptor in cell membrane by in vitro radioligand binding assay | Homo sapiens | 17 | ALA3232758 | cell-based format | Scientific Literature | |
3. | ALA3240642 | F | Antagonist activity at human OX2 receptor assessed as Ca2+ flux by FLIPR assay | Homo sapiens | 17 | ALA3232758 | single protein format | Scientific Literature | |
4. | ALA3240643 | F | Antagonist activity at human OX1 receptor assessed as Ca2+ flux by FLIPR assay | Homo sapiens | 17 | ALA3232758 | single protein format | Scientific Literature | |
5. | ALA3705095 | B | Radioligand Binding Assay: Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430. | Rattus norvegicus | 24 | ALA3639208 | single protein format | BindingDB Database | |
6. | ALA3707672 | B | Radioligand Binding Assay: Radioligand binding assay described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430. | Rattus norvegicus | 24 | ALA3639208 | single protein format | BindingDB Database | |
7. | ALA5244918 | P | Aqueous solubility of compound | 4 | ALA5244220 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA5244921 | B | Antagonist activity at human OX1R by FLIPR assay | Homo sapiens | 4 | ALA5244220 | single protein format | Scientific Literature | |
9. | ALA5244922 | B | Antagonist activity at human OX2R by FLIPR assay | Homo sapiens | 4 | ALA5244220 | single protein format | Scientific Literature | |
10. | ALA5244923 | A | Oral bioavailability in Sprague-Dawley rat at 2 mg/kg | Rattus norvegicus | 2 | ALA5244220 | organism-based format | Scientific Literature |