# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3243671 | P | Aqueous solubility of the compound in 2% DMSO at pH 7.4 by HPLC analysis | 32 | ALA3232888 | small-molecule physicochemical format | Scientific Literature | ||
2. | ALA3243672 | B | Agonist activity at Pseudomonas aeruginosa PqsR expressed in Escherichia coli DH5alpha assessed as induction of transcriptional activity at 5 uM by beta-galactosidase reporter gene assay relative to PQS | Pseudomonas aeruginosa | 30 | ALA3232888 | assay format | Scientific Literature | |
3. | ALA3243673 | B | Antagonist activity at Pseudomonas aeruginosa PqsR expressed in Escherichia coli DH5alpha assessed as inhibition of PQS-induced transcriptional activity at 50 nM by beta-galactosidase reporter gene assay relative to PQS | Pseudomonas aeruginosa | 31 | ALA3232888 | assay format | Scientific Literature | |
4. | ALA3243674 | B | Antagonist activity at Pseudomonas aeruginosa PqsR expressed in Escherichia coli DH5alpha assessed as inhibition of PQS-induced transcriptional activity at 5 uM by beta-galactosidase reporter gene assay relative to PQS | Pseudomonas aeruginosa | 31 | ALA3232888 | assay format | Scientific Literature | |
5. | ALA3243677 | B | Antagonist activity at Pseudomonas aeruginosa PqsR expressed in Escherichia coli DH5alpha assessed as inhibition of PQS-induced transcriptional activity by beta-galactosidase reporter gene assay relative to PQS | Pseudomonas aeruginosa | 10 | ALA3232888 | assay format | Scientific Literature | |
6. | ALA3243678 | F | Antivirulence activity in Pseudomonas aeruginosa PA14 assessed as reduction of extracellular level of PQS at 15 uM by UHPLC-MS/MS analysis relative to control | Pseudomonas aeruginosa | 7 | ALA3232888 | assay format | Scientific Literature | |
7. | ALA3243730 | F | Antivirulence activity in Pseudomonas aeruginosa PA14 assessed as reduction of extracellular level of pyocyanin at 15 uM relative to control | Pseudomonas aeruginosa | 7 | ALA3232888 | assay format | Scientific Literature | |
8. | ALA3243734 | F | Antivirulence activity in Pseudomonas aeruginosa PA14 assessed as reduction of extracellular level of pyocyanin | Pseudomonas aeruginosa | 2 | ALA3232888 | assay format | Scientific Literature | |
9. | ALA3243735 | P | Metal chelating activity of the compound assessed as CAS iron-chelation after 15 mins | 2 | ALA3232888 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA3243736 | A | Growth inhibition of Pseudomonas aeruginosa | Pseudomonas aeruginosa | 10 | ALA3232888 | organism-based format | Scientific Literature | |
11. | ALA4315940 | F | Inhibition of biofilm formation in Pseudomonas aeruginosa PAO1 at 10 uM incubated for 10 hrs by crystal violet staining based microtiter plate method relative to control | Pseudomonas aeruginosa | 11 | ALA4312019 | organism-based format | Scientific Literature | |
12. | ALA4315942 | F | Inhibition of biofilm formation in Pseudomonas aeruginosa PA14 at 10 uM incubated for 10 hrs by crystal violet staining based microtiter plate method relative to control | Pseudomonas aeruginosa | 11 | ALA4312019 | organism-based format | Scientific Literature | |
13. | ALA4315950 | B | Inhibition of human ERG | Homo sapiens | 15 | ALA4312019 | single protein format | Scientific Literature | |
14. | ALA4315989 | B | Inhibition of Pseudomonas aeruginosa PAO1 LasR transfected with lasB-GFP at 10 uM measured after 12 hrs by fluorescence based microtiter plate reader method relative to control | Pseudomonas aeruginosa PAO1 | 9 | ALA4312019 | assay format | Scientific Literature | |
15. | ALA4315990 | B | Inhibition of Pseudomonas aeruginosa PA14 PqsR transfected with pAW1-GFP at 10 uM measured after 12 hrs by fluorescence based microtiter plate reader method relative to control | Pseudomonas aeruginosa PA14 | 9 | ALA4312019 | assay format | Scientific Literature | |
16. | ALA4315998 | B | Inhibition of Pseudomonas aeruginosa PqsR at 5 uM relative to control | Pseudomonas aeruginosa | 1 | ALA4312019 | single protein format | Scientific Literature |