| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3240201 | B | Inhibition of full-length B-Raf V600E mutant (unknown origin) | Homo sapiens | 24 | ALA3232845 | assay format | Scientific Literature | |
| 2. | ALA3240202 | B | Inhibition of B-Raf V600E mutant in human Malme-3M cells assessed as basal ERK phosphorylation | Homo sapiens | 24 | ALA3232845 | cell-based format | Scientific Literature | |
| 3. | ALA3240203 | B | Inhibition of B-Raf (unknown origin) at 1 uM | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature | |
| 4. | ALA3240204 | A | Apparent permeability of the compound from apical to basolateral direction in pig LLC-PK1 cells | Sus scrofa | 2 | ALA3232845 | cell-based format | Scientific Literature | |
| 5. | ALA3240205 | A | Clearance in mouse microsomes | Mus musculus | 2 | ALA3232845 | assay format | Scientific Literature | |
| 6. | ALA3240206 | A | Clearance in mouse at 2.5 mg/kg, iv | Mus musculus | 2 | ALA3232845 | organism-based format | Scientific Literature | |
| 7. | ALA3240207 | A | Volume of distribution in mouse | Mus musculus | 2 | ALA3232845 | organism-based format | Scientific Literature | |
| 8. | ALA3240208 | A | AUC in mouse at 30 mg/kg, po | Mus musculus | 2 | ALA3232845 | organism-based format | Scientific Literature | |
| 9. | ALA3240209 | A | Oral bioavailability in mouse at 30 mg/kg | Mus musculus | 2 | ALA3232845 | organism-based format | Scientific Literature | |
| 10. | ALA3240210 | F | Antitumor activity against human LOX cells expressing B-Raf V600E mutant xenografted in nude mouse assessed as tumor growth inhibition at 30 mg/kg qd for 4 days measured on day 3 | Homo sapiens | 1 | ALA3232845 | organism-based format | Scientific Literature | |
| 11. | ALA3240211 | F | Antitumor activity against human LOX cells expressing B-Raf V600E mutant xenografted in nude mouse assessed as tumor growth inhibition at 30 mg/kg qd for 4 days measured on day 5 | Homo sapiens | 1 | ALA3232845 | organism-based format | Scientific Literature | |
| 12. | ALA3240212 | F | Antitumor activity against human LOX cells expressing B-Raf V600E mutant xenografted in nude mouse assessed as tumor growth inhibition at 30 mg/kg qd for 4 days measured on day 8 | Homo sapiens | 1 | ALA3232845 | organism-based format | Scientific Literature | |
| 13. | ALA3240213 | B | Inhibition of human AKT1 assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature | |
| 14. | ALA3240214 | B | Inhibition of human AKT2 assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature | |
| 15. | ALA3240215 | B | Inhibition of human AKT3 assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature | |
| 16. | ALA3240216 | B | Inhibition of human ALK assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature | |
| 17. | ALA3240217 | B | Inhibition of human ALK4 assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature | |
| 18. | ALA3240218 | B | Inhibition of human AMPKA1/B1/G1 assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | protein complex format | Scientific Literature | |
| 19. | ALA3240219 | B | Inhibition of human ARK5 assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature | |
| 20. | ALA3240220 | B | Inhibition of human AURKA assessed as enzyme activity at 1 uM relative to control | Homo sapiens | 1 | ALA3232845 | single protein format | Scientific Literature |
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