| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3243631 | Functional | Cytotoxicity against human HeLa cells assessed as cell viability after 24 hrs by MTS assay | Homo sapiens | 11 | ALA3232964 | cell-based format | Scientific Literature | |
| 2. | ALA3243632 | Functional | Cytotoxicity against human HeLa cells assessed as cell viability after 48 hrs by MTS assay | Homo sapiens | 11 | ALA3232964 | cell-based format | Scientific Literature | |
| 3. | ALA3243633 | ADME | Cytotoxicity against tumor promotion-sensitive mouse JB6 Cl41 cells assessed as cell viability after 48 hrs by MTS assay | Mus musculus | 11 | ALA3232964 | cell-based format | Scientific Literature | |
| 4. | ALA3243634 | Functional | Cytotoxicity against human HeLa cells assessed as inhibition of number of colonies formed in soft agar after 14 days by microscopic analysis | Homo sapiens | 11 | ALA3232964 | cell-based format | Scientific Literature | |
| 5. | ALA3243635 | Functional | Ratio of IC50 to INCC50 for human HeLa cells | Homo sapiens | 11 | ALA3232964 | cell-based format | Scientific Literature | |
| 6. | ALA3243636 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as early apoptotic cells at 2.5 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 6.71 +/- 4.41%) | Homo sapiens | 3 | ALA3232964 | cell-based format | Scientific Literature | |
| 7. | ALA3243637 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as late apoptotic/necrotic cells at 2.5 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 0.88 +/- 0.72%) | Homo sapiens | 3 | ALA3232964 | cell-based format | Scientific Literature | |
| 8. | ALA3243638 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as viable cells at 2.5 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 88.52 +/- 11%) | Homo sapiens | 3 | ALA3232964 | cell-based format | Scientific Literature | |
| 9. | ALA3243639 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as dead cells at 2.5 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 3.89 +/- 0.3%) | Homo sapiens | 3 | ALA3232964 | cell-based format | Scientific Literature | |
| 10. | ALA3243640 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as early apoptotic cells at 5 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 6.71 +/- 4.41%) | Homo sapiens | 3 | ALA3232964 | cell-based format | Scientific Literature | |
| 11. | ALA3243641 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as late apoptotic/necrotic cells at 5 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 0.88 +/- 0.72%) | Homo sapiens | 3 | ALA3232964 | cell-based format | Scientific Literature | |
| 12. | ALA3243642 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as viable cells at 5 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 88.52 +/- 11%) | Homo sapiens | 3 | ALA3232964 | cell-based format | Scientific Literature | |
| 13. | ALA3243643 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as dead cells at 5 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 3.89 +/- 0.3%) | Homo sapiens | 3 | ALA3232964 | cell-based format | Scientific Literature | |
| 14. | ALA3243644 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as early apoptotic cells at 10 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 6.71 +/- 4.41%) | Homo sapiens | 2 | ALA3232964 | cell-based format | Scientific Literature | |
| 15. | ALA3243645 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as late apoptotic/necrotic cells at 10 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 0.88 +/- 0.72%) | Homo sapiens | 2 | ALA3232964 | cell-based format | Scientific Literature | |
| 16. | ALA3243646 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as viable cells at 10 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 88.52 +/- 11%) | Homo sapiens | 2 | ALA3232964 | cell-based format | Scientific Literature | |
| 17. | ALA3243647 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as dead cells at 10 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 3.89 +/- 0.3%) | Homo sapiens | 2 | ALA3232964 | cell-based format | Scientific Literature | |
| 18. | ALA3243648 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as early apoptotic cells at 20 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 6.71 +/- 4.41%) | Homo sapiens | 1 | ALA3232964 | cell-based format | Scientific Literature | |
| 19. | ALA3243649 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as late apoptotic/necrotic cells at 20 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 0.88 +/- 0.72%) | Homo sapiens | 1 | ALA3232964 | cell-based format | Scientific Literature | |
| 20. | ALA3243682 | Functional | Induction of p53-independent apoptosis in human HeLa cells assessed as viable cells at 20 uM after 24 hrs by Annexin-V-FITC/propidium iodide double staining based flow cytometry (Rvb = 88.52 +/- 11%) | Homo sapiens | 1 | ALA3232964 | cell-based format | Scientific Literature |
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